820231-70-7Relevant academic research and scientific papers
Copper-mediated C-H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a cyanating agent
Qi, Chaorong,Hu, Xiaohan,Jiang, Huanfeng
supporting information, p. 7994 - 7997 (2017/07/22)
A copper-mediated direct C-H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a safe cyanating agent has been successfully developed by using molecular oxygen as the oxidant. The reaction tolerates a variety of functional groups and provides a facile and efficient method for the synthesis of a wide range of (hetero)aryl nitriles.
Co(III)-catalyzed C-H activation/formal SN-type reactions: Selective and efficient cyanation, halogenation, and allylation
Yu, Da-Gang,Gensch, Tobias,De Azambuja, Francisco,Vsquez-Cspedes, Suhelen,Glorius, Frank
supporting information, p. 17722 - 17725 (2015/02/19)
The first cobalt-catalyzed cyanation, halogenation, and allylation via C-H activation have been realized. These formal SN-type reactions generate valuable (hetero)aryl/alkenyl nitriles, iodides, and bromides as well as allylated indoles using a bench-stable Co(III) catalyst. High regio- and mono-selectivity were achieved for these reactions. Additionally, allylation proceeded efficiently with a turnover number of 2200 at room temperature, which is unprecedented for this Co(III) catalyst. Alkenyl substrates and amides have been successfully utilized in CpCo(III)-catalyzed C-H activation for the first time.
Copper-mediated direct aryl C-H cyanation with azobisisobutyronitrile via a free-radical pathway
Xu, Hao,Liu, Peng-Tang,Li, Yun-Hui,Han, Fu-She
supporting information, p. 3354 - 3357 (2013/07/26)
An unprecedented protocol for the copper-mediated direct cyanation of aryl C-H by employing 2,2′-azobisisobutyronitrile (AIBN) as a free radical "CN" source is presented. The protocol not only provides a more efficient pathway for the synthesis of aryl nitriles in terms of the yields and the loading amount of copper salts but also, more importantly, represents a novel strategy for aryl C-H cyanation via a CN free-radical mechanism as compared to the CN anion-participating protocols often reported.
Copper-catalyzed cyanation of arenes using benzyl nitrile as a cyanide anion surrogate
Jin, Jisong,Wen, Qiaodong,Lu, Ping,Wang, Yanguang
supporting information, p. 9933 - 9935 (2012/10/29)
The copper-catalyzed cyanation of arenes using benzyl nitrile as a cyanide anion surrogate furnishes aromatic nitriles in moderate to good yields. The cascade process involves a copper-catalyzed aerobic C-H oxidation, a retro-cyanohydrination, and a copper-catalyzed aerobic oxidative C-H functionalization. The Royal Society of Chemistry 2012.
Iron-mediated cyanation of methoxybenzene, indole, and 2-arylpyridine C-H bonds
Zhang, Guangyou,Lv, Guanglei,Pan, Changduo,Cheng, Jiang,Chen, Fan
supporting information; experimental part, p. 2991 - 2994 (2012/01/07)
An iron-mediated direct cyanation of indole and 2-arylpyridine C-H bonds is described. Notably, trimethoxybenzene reacted smoothly under the procedure, forming a C-CN bond via C-H bond cleavage without chelation assistance. Georg Thieme Verlag Stuttgart · New York.
Chelation-assisted palladium-catalyzed cascade bromination/cyanation reaction of 2-arylpyridine and 1-arylpyrazole C-H bonds
Jia, Xiaofei,Yang, Dongpeng,Wang, Wenhui,Luo, Fang,Cheng, Jiang
experimental part, p. 9470 - 9474 (2010/03/04)
(Chemical Equation Presented) A chelation-assisted palladium-catalyzed cascade bromination/cyanation reaction of 2-arylpyridine and 1-arylpyrazole C-H bonds has been developed. Notably, the reaction employs K3[Fe(CN) 6] as a safe and
Chelation-assisted palladium-catalyzed direct cyanation of 2-arylpyridine C-H bonds
Jia, Xiaofei,Yang, Dongpeng,Zhang, Shouhul,Cheng, Jiang
supporting information; experimental part, p. 4716 - 4719 (2009/12/22)
A chelation-assisted palladium-catalyzed ortho-cyanation of the sp 2 C-H bond by CuCN provided aromatic nitriles In moderate to good yields. Notably, the reaction could be conducted on a 10 mmol scale. The key Intermediate of the natural produc
METAL COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME
-
Page/Page column 66-67, (2010/11/08)
A metal-complex compound having a special structure containing metals such as iridium. An organic electroluminescence device which comprises at least one organic thin film layer sandwiched between a pair of electrode consisting of an anode and a cathode, wherein the organic thin film layer comprises the metal-complex compound, which emits light by applying an electric voltage between the pair of electrode. An organic EL device employing the novel metal-complex compound emits various phosphorous light including blue light having an enhanced current efficiency and prolonged lifetime.
