820241-40-5

Upstream product

• 452056-79-0 N-{4-[2-cyano-2-(4-fluorophenyl)acetyl]pyridin-2-yl}acetamide 
• 452056-82-5 N-{4-[2-(4-fluorophenyl)-2-hydroxyliminoacetyl]pyridin-2-yl}acetamide 
• 452056-81-4 N-{4-[2-(4-fluorophenyl)acetyl]pyridin-2-yl}acetamide 
• 452056-80-3 1-(2-aminopyridin-4-yl)-2-(4-fluorophenyl)ethanone 
• 54221-95-3 2-(acetylamino)isonicotinic acid 
• 459-22-3 4-fluorophenylacetonitrile 
• 820241-18-7 N-{4-[5-(4-fluorophenyl)-1-oxy-3-(3-methoxypropyl)-3H-imidazol-4-yl]pyridin-2-yl}acetamide 

Downstream Products

• 820241-55-2 N-{4-[5-(4-fluorophenyl)-3-(3-methoxypropyl)-2-methylsulfanyl-3H-imidazol-4-yl]pyridin-2-yl}acetamide 

Relevant academic research and scientific papers

Tetrasubstituted imidazole inhibitors of cytokine release: Probing substituents in the N-1 position

We prepared novel 1,2,4,5-tetrasubstituted imidazole derivatives with high anti-inflammatory activity by using our previously described regiospecific synthesis. Systematic optimization of the imidazole N-1 substituent resulted in compound 9b that potently