820244-79-9

Upstream product

• 2937-50-0 Allyl chloroformate 
• 569686-87-9 MGS0039 

Downstream Products

• 820244-80-2 (1'R,2'R,3'R,5'R,6'R)-3'-(3,4-dichlorobenzyloxy)-6'-fluoro-3-allyloxycarbonyl-5-oxooxazinone-4-spiro-2'-bicyclo[3.1.0]hexane-6'-carboxylic acid 

Relevant academic research and scientific papers

NOVEL COMPOUNDS AND COMPOSITIONS THEREOF FOR TREATING NERVOUS SYSTEM DISORDERS

The present invention relates to a novel compound, methods of synthesizing the compound, compositions containing the compound, and methods for using the compound or composition to treat and/or prevent diseases and/or conditions of the central and peripher

2-AMINOBICYCLO 3.1.0 HEXANE-2,6-DICARBOXYLIC ESTER DERIVATIVE

A drug effective for the treatment and prevention of psychiatric disorders such as schizophrenia, anxiety and related ailments thereof, depression, bipolar disorder and epilepsy. The drug antagonizes the action of group II metabotropic glutamate receptors

Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicar boxylic acid (MGS0039): A potent and orally active group II mGluR antagonist with antidepressant-like potential

3-(3,4-Dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicar boxylic acid 5 (MGS0039) is a highly selective and potent group II metabotropic glutamate receptor (mGluR) antagonist (antagonist activities for mGluR2; IC50 = 20.0 nM, mG