82026-03-7 Usage
Uses
Used in Pharmaceutical Applications:
[(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-3,9-dihydroxy-9-(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalen-4-yl]methyl acetate is used as a potential pharmaceutical agent due to its structural and stereochemical features, which may contribute to its bioactivity and medicinal properties.
Used in Medicinal Chemistry Research:
[(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-3,9-dihydroxy-9-(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalen-4-yl]methyl acetate is used as a subject of study in medicinal chemistry, where its properties and potential applications are being investigated. The research aims to understand its interactions with biological targets and its potential therapeutic effects.
Used in Drug Development:
[(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-3,9-dihydroxy-9-(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalen-4-yl]methyl acetate may be utilized in the development of new drugs, particularly those targeting various diseases and conditions. Its unique structure and bioactivity make it a promising candidate for drug discovery and design.
Used in Chemical Synthesis:
[(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-3,9-dihydroxy-9-(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalen-4-yl]methyl acetate can be used as a starting material or intermediate in the synthesis of other complex organic molecules, potentially leading to the creation of novel pharmaceuticals or chemical products with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 82026-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,0,2 and 6 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 82026-03:
(7*8)+(6*2)+(5*0)+(4*2)+(3*6)+(2*0)+(1*3)=97
97 % 10 = 7
So 82026-03-7 is a valid CAS Registry Number.
82026-03-7Relevant academic research and scientific papers
Microbial Transformations of Natural Antitumor Agents. 21. Conversions of Aphidicolin
Ipsen, John,Fuska, Jan,Foskova, A.,Rosazza, John P.
, p. 3278 - 3282 (2007/10/02)
Microbial transformations have been employed as a means of preparing analogues of the diterpene aphidicolin.Microbial transformation products were initially identified by thin-layer chromatography of fermentation extracts and then were prepared by larger scale incubations.Each microbial metabolite was subjected to structure elucidation employing carbon-13 and proton NMR, high-resolution mass spectrometry, and infrared analysis.Metabolites were identified as 3α-acetoxy-16,17,18-trihydroxyaphidicolane, 18-acetoxy-3α,16,17-trihydroxyaphidicolane,3α,16,17-trihydroxyaphidicolan-18-oate, 16,17,18-trihydroxyaphidicolan-3-one, 3β,16,17,18-tetrahydroxyaphidicolane, and 3α,6β,16,17,18-pentahydroxyaphidicolane.The availability of the microbial metabolites enabled the near complete elucidation of the carbon-13 NMR spectrum of aphidicolin.Biological evaluations of these compounds were made by using in vivo and in vitro techniques.None of the metabolites were active in an in vivo antitumor test system, while all of the compounds inhibited the uptake of the thymidine to P-388 leukemic cells in vitro.
