820260-55-7Relevant academic research and scientific papers
Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicar boxylic acid (MGS0039): A potent and orally active group II mGluR antagonist with antidepressant-like potential
Yasuhara, Akito,Nakamura, Masato,Sakagami, Kazunari,Shimazaki, Toshiharu,Yoshikawa, Ryoko,Chaki, Shigeyuki,Ohta, Hiroshi,Nakazato, Atsuro
, p. 4193 - 4207 (2007/10/03)
3-(3,4-Dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicar boxylic acid 5 (MGS0039) is a highly selective and potent group II metabotropic glutamate receptor (mGluR) antagonist (antagonist activities for mGluR2; IC50 = 20.0 nM, mG
