82040-72-0Relevant academic research and scientific papers
Multicomponent synthesis of 4-aryl-NH-1,2,3-triazoles in the presence of Al-MCM-41 and sulfated zirconia
Vergara-Arenas, Blanca Ivonne,Lomas-Romero, Leticia,ángeles-Beltrán, Deyanira,Negrón-Silva, Guillermo Enrique,Gutiérrez-Carrillo, Atilano,Lara, Víctor Hugo,Morales-Serna, José Antonio
supporting information, p. 2690 - 2694 (2017/06/23)
The acid properties of Al-MCM-41 and sulfated zirconia were used to develop a strategy for the synthesis of 4-aryl-NH-1,2,3-triazoles via a multicomponent reaction involving various benzaldehydes, sodium azide and nitromethane. The efficiency of the process is analysed from the perspective of the difference in acids among the catalysts used.
Synthesis of 3-arylindole derivatives from nitroalkane precursors
Huang, Chia-Yu,Kuo, Chun-Wei,Konala, Ashok,Yang, Tang-Hao,Lin, Lyu,Chen, Yu-Wen,Kavala, Veerababurao,Yao, Ching-Fa
, p. 96049 - 96056 (2016/10/25)
3-Arylindole derivatives were synthesized by Cu(i) catalysed intramolecular Ullmann coupling of 2-bromoarylaminoalkanes. 2-Bromoarylaminoalkanes were synthesized from 2-bromoarylnitroalkanes, which in turn prepared through AlCl3-mediated Friede
Synthesis of β-nitrostyrenes in the presence of sulfated zirconia and secondary amines
González-Olvera,Vergara-Arenas,Negrón-Silva,Angeles-Beltrán,Lomas-Romero,Gutiérrez-Carrillo,Lara,Morales-Serna
, p. 99188 - 99192 (2015/12/05)
A simple and efficient protocol for the synthesis of β-nitrostyrenes has been achieved by the use of sulfated zirconia-secondary amine (piperidine, pyrrolidine, proline or prolinol) cooperative systems. The condensation of different aldehydes and nitromethane demonstrates the efficiency of this process, which does not require high-temperature reactivation for the reuse of the catalytic material.
Stereoselective synthesis of indolines via organocatalytic thioester enolate addition reactions
Kolarovic, Andrej,Kaeslin, Alexander,Wennemers, Helma
supporting information, p. 4236 - 4239 (2014/10/15)
A straightforward stereoselective synthesis route to indolin-3-yl acetates has been developed using organocatalytic addition reactions of monothiomalonates to ortho-bromo nitrostyrenes as the key step. The addition products of this highly stereoselective one-pot addition-deprotection-decarboxylation sequence were easily further converted to the target indolin-3-yl acetates, via an intramolecular Buchwald-Hartwig coupling reaction. The route provided indolin-3-yl acetates bearing tertiary and exocyclic quarternary stereogenic centers in excellent stereoselectivities and overall yields of 34-83%.
Synthesis of vinylphosphonates and its first exploration of bioactivity
Li, Sheng-Nan,Xu, Lan-Ting,Chenb, Yue,Lia, Ju-Lian,He, Ling
experimental part, p. 416 - 422 (2012/05/04)
Phosphonation of β-nitro-alkene with triethyl phosphite was achieved under microwave irradiation using CH2Cl2 as the solvent in the absence of catalyst with moderate to high yields (up to 90%). This method of formation of carbonphosphor bonds is simple, mild, convenient and effective. Synchronously, a number of vinylphosphonates derivatives were synthesized and evaluated biologically preliminary.
