82042-26-0

Basic information

• Product Name: 2,6-epiperhydrohistrionicotoxin
• CAS NO: 82042-26-0
• Molecular Weight: 295.509
• Mol File: 82042-26-0.mol

Chemical Properties

• CAS DataBase Reference: 2,6-epiperhydrohistrionicotoxin(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-epiperhydrohistrionicotoxin(82042-26-0)
• EPA Substance Registry System: 2,6-epiperhydrohistrionicotoxin(82042-26-0)

Safety Data

• Hazardous Substances Data: 82042-26-0(Hazardous Substances Data)

Upstream product

• 119203-94-0 1-benzylperhydrohistrionicotoxin 
• 62026-51-1 2-epi-8-oxo-perhydrohistrionicotoxin 
• 36823-78-6 2,2-bis-(3-chloro-propyl)-[1,3]dioxolane 
• 62026-27-1 3-(4-Amino-nonyl)-2-butyl-cyclohex-2-enone 
• 344752-45-0 2,2-Bis-[3-(2-pentyl-[1,3]dithian-2-yl)-propyl]-[1,3]dioxolane 
• 119203-94-0 1-benzyl-2,6-epiperhydrohistrionicotoxin 
• 32362-97-3 2-pentylcyclohexanone 
• 84460-49-1 7-pentylhexahydroazepin-2-one 
• 122624-02-6 1-benzyl-7-pentylhexahydroazepin-2-one 
• 122624-10-6 methyl 1-benzyl-7-pentyl-4,5,6,7-tetrahydro-1H-azepine-3-carboxylate 
• 122624-05-9 methyl 1-benzyl-7-pentyl-2-thioxohexahydroazepine-3-carboxylate 
• 122624-27-5 (2R^*,6R^*)-1-benzyl-7-butyl-2-pentyl-1-azaspiro<5.5>undec-7-ene 
• 122624-25-3 (2R^*,6R^*)-1-benzyl-7-butyl-2-pentyl-1-azaspiro<5.5>undec-7-en-9-one 
• 122624-26-4 (2R,6R)-1-Benzyl-7-butyl-2-pentyl-1-aza-spiro[5.5]undec-7-en-9-ol 

Relevant articles and documents

A two-directional synthesis of (+/-)-perhydrohistrionicotoxin.

An entirely two-directional synthesis of (+/-)-perhydrohistrionicotoxin is presented, utilizing a tandem oxime formation/Michael addition/[3 + 2] cycloaddition as the key step. This approach also constitutes formal syntheses of (+/-)-histrionicotoxin and (+/-)-histrionicotoxin 235A.

A Novel and Highly Stereoselective Approach to Aza-Spirocycles. A Short Total Synthesis of 2-epi-(±)-Perhydrohistrionicotoxin and an Unprecedented Decarboxylation of 2-Pyrones

(Matrix Presented) A novel and highly stereoselective synthesis of aza-spirocycles is described. An application of this methodology is illustrated as a short and concise total synthesis of 2-epi-(±)-perhydrohistrionicotoxin with high diastereomeric contro

Highly Stereoselective Ring Contraction of Heterocyclic Enamines: Total Synthesis of Perhydrohistrionicotoxin and Its 2,6-Epimer

The total syntheses of perhydrohistrionicotoxin (PHTX) and its 2,6-epimer in which the pentyl group, introduced in the early stages, controls the relative configuration of C6 in a highly stereoselective manner are described.Seven-membered heterocyclic ena

THE STEREOCHEMISTRY OF SPIROPIPERIDINE CYCLIZATIONS (HISTRIONICOTOXIN, PART I)

The spirocyclization of straight-chain triketo-intermediates, similar to possible biogenetic precursors of histrionicotoxin, is shown to be stereoselective, generating the non-natural configuration at C-2.Aiming at an sp2-center in this positio