82080-04-4Relevant articles and documents
Synthesis of methionine containing peptides related to native chemical ligation
Pachamuthu, Kandasamy,Schmidt, Richard R.
, p. 659 - 662 (2007/10/03)
Methionine chemical ligation is based on a convenient direct thioester formation at the C-terminus of the ligation site, on homocysteine reduction with dithiothreitol in order to liberate the mercapto group of the homocysteine residue at the N-terminus, and on chemoselective S-methylation with methyl iodide.