82080-83-9Relevant academic research and scientific papers
Diastereoselective α Allylation of Secondary and Tertiary Thioamides via Thio-Claisen Rearrangement. A Structural Proof of Z Secondary Thioamide Dianions and Z Tertiary Thioamide Anions
Tamaru, Y.,Furukawa, Y.,Mizutani, M.,Kitao, O.,Yoshida, Z.
, p. 3631 - 3639 (2007/10/02)
Highly diastereoselective α allylation of secondary and tertiary thioamides is achieved by making use of thio-Claisen rearrangement.From the correlation between the diastereoselectivities in products and the structures of allylating agents, the Z structures of secondary thioamide dianion (ca. 100percent Z) and tertiary thioamide anion (>97percent Z) are concluded.
