82081-93-4Relevant academic research and scientific papers
Backbone-Enabled Directional Peptide Macrocyclization through Late-Stage Palladium-Catalyzed δ-C(sp2)?H Olefination
Bai, Zengbing,Cai, Chuangxu,Yu, Zonglun,Wang, Huan
, p. 13912 - 13916 (2018)
C?H activation methods for peptide macrocyclization have the potential to provide peptidomimetics and cyclic peptides with expanded structural diversity. Now, a highly versatile peptide macrocyclization strategy via late-stage palladium-catalyzed δ-C(sps
METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE COMPOUND, AND CATALYST AND FLOW PRODUCTION SYSTEM
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Paragraph 0081-0087, (2021/09/03)
PROBLEM TO BE SOLVED: To provide a new production method that allows a dehydration condensation reaction between carboxylic acid and amine, and a catalyst. SOLUTION: A method for producing a carboxylic acid amide compound includes the step for causing a r
The greening of peptide synthesis
Lawrenson, Stefan B.,Arav, Roy,North, Michael
supporting information, p. 1685 - 1691 (2017/06/07)
The synthesis of peptides by amide bond formation between suitably protected amino acids is a fundamental part of the drug discovery process. However, the required coupling and deprotection reactions are routinely carried out in dichloromethane and DMF, b
Alanine scan of [L-Dap2]ramoplanin A2 aglycon: Assessment of the importance of each residue
Nam, Joonwoo,Shin, Dongwoo,Rew, Yosup,Boger, Dale L.
, p. 8747 - 8755 (2008/02/13)
In efforts that define the importance of each residue and that identify key regions of the molecule, an alanine scan of the ramoplanin A2 aglycon, a potent antibiotic that inhibits bacterial cell wall biosynthesis, is detailed. As a consequence of both it
Synthesis of immunoaduvant conjugates with HIV-derived peptide inducing peptide-specific antibody
Maruyama,Kurimura,Achiwa
, p. 1709 - 1711 (2007/10/02)
MDP and lipopeptide analog conjugates inducing HIV-derived peptide-specific antibody without adding further macromolecular carriers or adjuvants were synthesized.
