820976-83-8

Basic information

• Product Name: Benzenepropanoic acid, ba-hydroxy-2-methyl-, ethyl ester, (baS)- (9CI)
• Synonyms: Benzenepropanoicacid,bta-hydroxy-2-methyl-,ethylester,(btaS)-(9CI);Benzenepropanoic acid, ba-hydroxy-2-methyl-, ethyl ester, (baS)- (9CI)
• CAS NO: 820976-83-8
• Molecular Formula: C12H16O3
• Molecular Weight: 208.25364
• Product Categories: METHYL
• Mol File: 820976-83-8.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanoic acid, ba-hydroxy-2-methyl-, ethyl ester, (baS)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, ba-hydroxy-2-methyl-, ethyl ester, (baS)- (9CI)(820976-83-8)
• EPA Substance Registry System: Benzenepropanoic acid, ba-hydroxy-2-methyl-, ethyl ester, (baS)- (9CI)(820976-83-8)

Safety Data

• Hazardous Substances Data: 820976-83-8(Hazardous Substances Data)

Upstream product

• 51725-82-7 ethyl (2-methylbenzoyl)acetate 
• 1252813-54-9 (S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(o-tolyl)propanoate 
• 24393-48-4 ethyl trans-2-methylcinnamate 
• 141-78-6 ethyl acetate 
• 529-20-4 2-methylphenyl aldehyde 
• 4071-88-9 trimethylsilanyl-acetic acid ethyl ester 

Relevant articles and documents

Tridentate nitrogen phosphine ligand containing arylamine NH as well as preparation method and application thereof

The invention discloses a tridentate nitrogen phosphine ligand containing arylamine NH as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis. The tridentate nitrogen phosphine ligand disclosed by the invention is the first case of tridentate nitrogen phosphine ligand containing not only a quinoline amine structure but also chiral ferrocene at present, a noble metal complex of the type of ligand shows good selectivity and extremely high catalytic activity in an asymmetric hydrogenation reaction, meanwhile, a cheap metal complex of the ligand can also show good selectivity and catalytic activity in the asymmetric hydrogenation reaction, and is very easy to modify in the aspects of electronic effect and space structure, so that the ligand has huge potential application value. A catalyst formed by the ligand and a transition metal complex can be used for catalyzing various reactions, can be used for synthesizing various drugs, and has important industrial application value.

Efficient P-Chiral Biaryl Bisphosphorus Ligands for Palladium-Catalyzed Asymmetric Hydrogenation

A series of structurally novel P-chiral biaryl bisphosphorus ligands L1-L5 (BABIBOPs) are developed, providing high efficiency for the first time in palladium-catalyzed asymmetric hydrogenation of β-aryl and β-alkyl substituted β-keto esters. With the Pd-L3 (iPr-BABIBOP) catalyst, a series of chiral β-hydroxyl carboxylic esters are formed in excellent enantioselectivities (up to>99% ee) and yields at catalyst loading as low as 0.01 mol%.

A chiral three teeth PNN ligand and its asymmetric hydrogenation reaction in the application of the

The invention discloses a chiral tridentate PNN ligand and application of the same in asymmetric hydrogenation and similar reactions. The tridentate nitrogen phosphine ligand disclosed in the invention has been the first reported nitrogen phosphine ligand containing chiral oxazoline so far and has been successfully applied to high-efficiency and high-selectivity hydrogenation and similar reactions of ketone and imine salts. Compared with other ligand, the ligand provided by the invention is simpler in synthetic route, higher in yield and environment-friendlier; moreover, the metal complex of the ligand shows better selectivity and a higher turn-over number in asymmetric hydrogenation. An iridium complex of the chiral tridentate PNN ligand has successfully realized asymmetric reduction of beta-ketone ester into beta-alcohol ester (which is a raw material for synthesis of molecular drugs duloxetine and atomoxetine), asymmetric hydrogenation of alpha-hydroxyacetophenone into alpha-hydroxyphenylethyl alcohol and asymmetric hydrogenation of acetophenone into phenylethyl alcohol, which is of important significance to production of the medical industry.