820994-17-0

Upstream product

• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 71461-30-8 (S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester 
• 6216-63-3 N-Cbz-Prolinol 

Downstream Products

• 543690-37-5 (1R,2S,7aS)-1,2-hydroxypyrrolizidine 
• 820994-20-5 methyl (2R,3S)-2,3-dihydroxy-3-[(2'S)-N-benzyloxycarbonylpyrrolidin-2'-yl]propanoate 
• 820994-19-2 methyl (2S,3R)-2,3-dihydroxy-3-[(2'S)-N-benzyloxycarbonylpyrrolidin-2'-yl]propanoate 

Relevant academic research and scientific papers

Polyhydroxylated pyrrolizidines. Part 5: Stereoselective synthesis of 1,2-dihydroxypyrrolizidines as a model for the preparation of densely polyhydroxylated pyrrolizidines

The reaction of N-benzyloxycarbonyl-l-prolinal 5 with (methoxycarbonylmethylene)triphenylphosphorane in CH2Cl2 afforded methyl (E)-3-[(2′S)-N-benzyloxycarbonylpyrrolidin-2′-yl] propenoate 7. When the reaction was performed in MeOH, a

Diastereoselective Epoxidation of cis-4-Amino Allylic Alcohol with m-Chloroperbenzoic acid. An Efficient Synthesis of Statine

High diastereoselective epoxidation of cis-4-amino allylic alcohol (3) with m-chloroperbenzoic acid is described and the reaction is applied to the stereoselective synthesis of the β-hydroxy-γ-amino acid, statine.