821006-43-3Relevant articles and documents
Total synthesis of ustiloxin D and considerations on the origin of selectivity of the asymmetric allylic alkylation
Sawayama, Andrew M.,Tanaka, Hiroko,Wandless, Thomas J.
, p. 8810 - 8820 (2007/10/03)
As part of investigations into cell cycle checkpoint inhibitors, an asymmetric synthesis of the antimitotic natural product, ustiloxin D, has been completed. A salen-Al-catalyzed aldol reaction was employed to construct a chiral oxazoline 9 (99% yield, 98