82111-35-1

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 1439-07-2 trans-Stilbene oxide 
• 82032-22-2 N-(Phenylethyl)-1-phenyl-1-benzoylmethylamine hydrochloride 

Downstream Products

• 82087-17-0 (2R, 4R, 5S, 3'R)-N,N-bis(1-phenylethyl)-1,2-diphenyl-2-aminoethanol 
• 40648-92-8 (R,R)-(+)-bis[alpha-methylbenzyl]amine hydrochloride 
• 82087-16-9 (2S, 4R, 5S, 3'R)-(-)-N-(1-phenylethyl)-2,4,5-triphenyloxazolidine 
• 99390-10-0 4-(R-1-phenylethyl)-(5R₆S)-5,6-diphenylmorpholine-2,3-dione 

Relevant academic research and scientific papers

Indium-mediated Barbier-type allylation of aldehydes as a convenient method for the highly enantioselective synthesis of homoallylic alcohols

We report a general method for the indium-mediated Barbier-type enantioselective allylation of both aromatic and aliphatic aldehydes using commercially available (1S,2R)-(+)-2-amino-1,2-diphenylethanol as a chiral auxiliary. Using only two equivalents of allyl bromide, excellent yields and very good to excellent enantioselectivities are obtained. To our knowledge, the enantioselectivities reported herein are the highest obtained for indium-promoted allylations of carbonyl compounds.

Asymmetric hydrogenation of chiral vinyloxazaborolidines under ambient conditions

Novel homochiral vinyloxazaborolidines have been synthesized and subsequently hydrogenated using palladium on carbon under ambient conditions to produce, after oxidation of the boronate group, enantiomerically enriched secondary alcohols (up to 20% ee). H

THE STEREOSELECTIVE REDUCTION OF α-AMINODEOXYBENZOIN DERIVATIVES WITH SODIUM BOROHYDRIDE

Total stereoselectivity is observed in the sodium borohydride reduction of α-aminodeoxybenzoins and their hydrochlorides in various hydroxylic solvents.RS-SR isomer (erythro) was the only aminoalcohol obtained.