82111-35-1

Basic information

• Product Name: (1S,2R)-1,2-Diphenyl-2-(1-phenyl-ethylamino)-ethanol
• CAS NO: 82111-35-1
• Molecular Weight: 317.431
• Mol File: 82111-35-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R)-1,2-Diphenyl-2-(1-phenyl-ethylamino)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1,2-Diphenyl-2-(1-phenyl-ethylamino)-ethanol(82111-35-1)
• EPA Substance Registry System: (1S,2R)-1,2-Diphenyl-2-(1-phenyl-ethylamino)-ethanol(82111-35-1)

Safety Data

• Hazardous Substances Data: 82111-35-1(Hazardous Substances Data)

Upstream product

• 82032-22-2 N-(Phenylethyl)-1-phenyl-1-benzoylmethylamine hydrochloride 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 1439-07-2 trans-Stilbene oxide 

Downstream Products

• 99390-10-0 4-(R-1-phenylethyl)-(5R₆S)-5,6-diphenylmorpholine-2,3-dione 
• 82087-16-9 (2S, 4R, 5S, 3'R)-(-)-N-(1-phenylethyl)-2,4,5-triphenyloxazolidine 
• 40648-92-8 (R,R)-(+)-bis[alpha-methylbenzyl]amine hydrochloride 
• 82087-17-0 (2R, 4R, 5S, 3'R)-N,N-bis(1-phenylethyl)-1,2-diphenyl-2-aminoethanol 

Relevant articles and documents

Indium-mediated Barbier-type allylation of aldehydes as a convenient method for the highly enantioselective synthesis of homoallylic alcohols

We report a general method for the indium-mediated Barbier-type enantioselective allylation of both aromatic and aliphatic aldehydes using commercially available (1S,2R)-(+)-2-amino-1,2-diphenylethanol as a chiral auxiliary. Using only two equivalents of allyl bromide, excellent yields and very good to excellent enantioselectivities are obtained. To our knowledge, the enantioselectivities reported herein are the highest obtained for indium-promoted allylations of carbonyl compounds.

THE STEREOSELECTIVE REDUCTION OF α-AMINODEOXYBENZOIN DERIVATIVES WITH SODIUM BOROHYDRIDE

Total stereoselectivity is observed in the sodium borohydride reduction of α-aminodeoxybenzoins and their hydrochlorides in various hydroxylic solvents.RS-SR isomer (erythro) was the only aminoalcohol obtained.