82112-44-5

Basic information

• Product Name: (4R,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene
• Synonyms: (4R,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene
• CAS NO: 82112-44-5
• Molecular Weight: 388.595
• Mol File: 82112-44-5.mol

Chemical Properties

• CAS DataBase Reference: (4R,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene(82112-44-5)
• EPA Substance Registry System: (4R,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene(82112-44-5)

Safety Data

• Hazardous Substances Data: 82112-44-5(Hazardous Substances Data)

Upstream product

• 5389-87-7 1-chloro-3,7-dimethylocta-2,6-diene 
• 73838-25-2 (3-thienyl)-p-toluenesulfonyl methane 
• 82112-39-8 3-[(E)-4,8-Dimethyl-1-(toluene-4-sulfonyl)-nona-3,7-dienyl]-thiophene 

Relevant articles and documents

Aromatic Resin Acid Ring System via Detosylation of Polyene Cyclization Derived Products

An efficient three-step strategy into resin acid type systems III and their cis isomers VI is presented.As illustrated by five exampels, the method involves geranylation of sulfones 7a-c and nerylation of 7a,b to 8a-c and 9a,b, respectively.Subsequent FSO3H-SO2-promoted polyene cyclizations proceed stereospecifically and with asymmetric induction to produce epimeric diastereomers 10a-c/11a-c and 12a,b/13a,b in 60:40 and 70:30 ratios.Each epimeric set undergoes Dibal-H-mediated detosylation to provide diastereomeric compounds 15-19 in high yields.