82126-46-3Relevant academic research and scientific papers
Original Syntheses of Carbonyl Compounds and gem-Dihalocyclopropanes from β-Hydroxylalkylselenides
Krief,A.,Laboureur, J. L.,Dumont, W.
, p. 1549 - 1552 (2007/10/02)
β-hydroxyalkylselenides possessing two alkyl substituents on the carbon bearing the selenyl moiety react with dihalocarbenes generated from haloforms and thallous ethoxide or under phase transfer catalysis to produce ring enlarged ketones as the sole product in the first case, as the main product in the second.The reaction takes another course when the dihalocarbenes generated from haloforms and tBuOK or from trihalomethylphenylmercury are employed and leads inter alias to dihalocyclopropanes.
NEW METHOD FOR THE RING ENLARGEMENT OF CYCLIC KETONES
Labar, D.,Laboureur, J. L.,Krief, A.
, p. 983 - 986 (2007/10/02)
A simple two step procedure which allows the ring enlargement of cyclic ketones is disclosed which takes advantage of the high nucleophilicity of α-selenoalkyllithiums towards carbonyl compounds and of a novel transposition reaction which occurs on the resulting β-hydroxyselenides.
