82127-18-2Relevant academic research and scientific papers
CYCLIZATION REACTIONS OF NITRILES. 2-ARYL-3-(2-THENOYL)-1,1-DICYANOPROPANES AND PYRIDINE DERIVATIVES BASED ON THEM
Sharanin, Yu. A.,Promonenkov, V. K.,Shestopalov, A. M.
, p. 548 - 556 (2007/10/02)
In the reaction of 1,1,1-trifluoro-3-(2-thenoyl)acetone with arylidenemalononitriles acid cleavage of the products from Michael addition takes place with the formation of 2-aryl-3-(2-thenoyl)-1,1-dicyanopropanes.They were used for the synthesis of 4-aryl-2-bromo-6-(2-thienyl)-3-cyanopyridines and 4-aryl-6-(2-thienyl)-3-cyano-2(1H)-pyridinethiones and condensed heterocyclic compounds based on them.
