82131-02-0Relevant academic research and scientific papers
SYNTHESIS OF 2(3H)-BENZOFURANONE DERIVATIVES BY COPPER(I)-PROMOTED SUBSTITUTION REACTIONS OF ACTIVE METHYLENE CARBANIONS
Setsune, Jun-ichiro,Ueda, Takashi,Shikata, Katsumi,Matsukawa, Kimihiro,Iida, Toshiya,Kitao, Teijiro
, p. 2647 - 2656 (2007/10/02)
Activation of soft carbanions by copper(I) in the substitution reaction toward aryl halides and allyl halides was demonstrated.Derivatives of 2(3H)-benzofuranones (2, 14-18) were prepared in a one-pot procedure by the reaction of copper(I) diethyl malonat
SYNTHESIS OF BENZOFURAN-2-ONE DERIVATIVES BY COPPER(I)-PROMOTED COUPLING REACTIONS OF o-BROMOPHENOL WITH ACTIVE METHYLENE COMPOUNDS
Setsune, Jun-ichiro,Matsukawa, Kimihiro,Kitao, Teijiro
, p. 663 - 666 (2007/10/02)
Summary: Treatment of o-bromophenoxide anion with sodium salts of active methylene compounds in the presence of copper(I) bromide in dioxane afforded benzofuran-2-one derivatives.The phenoxide group of o- and p-bromophenol activates the coupling reaction.
