82158-24-5

Basic information

• Product Name: 1-benzofuran-2-yl(2-methylphenyl)methanol
• CAS NO: 82158-24-5
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.2812
• Mol File: 82158-24-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 393.8°C at 760 mmHg
• Flash Point: 192°C
• Density: 1.189g/cm³
• Vapor Pressure: 6.57E-07mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 1-benzofuran-2-yl(2-methylphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzofuran-2-yl(2-methylphenyl)methanol(82158-24-5)
• EPA Substance Registry System: 1-benzofuran-2-yl(2-methylphenyl)methanol(82158-24-5)

Safety Data

• Hazardous Substances Data: 82158-24-5(Hazardous Substances Data)

Upstream product

• 533-58-4 2-Iodophenol 
• 139416-71-0 1-(o-tolyl)prop-2-yn-1-ol 

Relevant articles and documents

Enantioselective reduction of benzofuranyl aryl ketones

Enantioselective transfer hydrogenation of benzofuranyl aryl ketones proceeds with moderate to good enantioselectivity even when the aryl group is not sterically differentiated by ortho-substituents. The best results are obtained with substrates that are functionalised by electron-withdrawing aryl groups that contrast with the electron-rich benzofuran, which is consistent with [Ru-ArC-H]·Ar π interactions acting as a control element. Enantioselective pressure hydrogenation gives lower enantioselectivity irrespective of electronic effects, unless the aryl group is ortho-substituted, in which case up to 86% ee can be realised. Georg Thieme Verlag Stuttgart - New York.

Palladium-catalysed Heteroannulation of Acetylenic Compounds: a Facile Method for the Synthesis of Benzofurans

A convenient and general method for the synthesis of benzofurans from o-iodophenol and acetylenic compounds under palladium-catalysed conditions is described.