82173-06-6

Upstream product

• 16042-25-4 1H-imidazole-2-carboxylic acid 
• 95-53-4 o-toluidine 

Downstream Products

• 1403942-54-0 1-amino-N-o-tolyl-1H-imidazole-2-carboxamide 
• 1403942-55-1 2-(chloromethyl)-3-o-tolylimidazo[1,2-f][1,2,4]triazin-4(3H)-one 
• 1403946-32-6 2-((6-amino-9H-purin-9-yl)methyl)-3-o-tolylimidazo[1,2-f][1,2,4]triazin-4(3H)-one 

Relevant academic research and scientific papers

PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

Pyrrolotriazinone derivatives as PI3K inhibitors

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks)