82174-08-1

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-(TRIFLUOROMETHYLTHIO)BENZYL ALCOHOL is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides.
Used in Organic Synthesis:
3-(TRIFLUOROMETHYLTHIO)BENZYL ALCOHOL is utilized as a reagent in organic synthesis, playing a crucial role in the formation of complex organic molecules.
Used as a Solvent in Chemical Reactions:
3-(TRIFLUOROMETHYLTHIO)BENZYL ALCOHOL is employed as a solvent in a range of chemical reactions, facilitating the process and improving the efficiency of these reactions.
Used in the Development of Advanced Materials:
3-(TRIFLUOROMETHYLTHIO)BENZYL ALCOHOL has potential applications in the development of advanced materials, indicating its versatility and importance in material science.
Used in the Production of Fine Chemical Intermediates:
3-(TRIFLUOROMETHYLTHIO)BENZYL ALCOHOL is used in the production of fine chemical intermediates, which are essential for the synthesis of specialty chemicals and high-value products.

Upstream product

• 87199-15-3 [3-(hydroxymethyl)phenyl]boronic acid 
• 946-65-6 3-(trifluoromethylthio)benzoic acid 

Downstream Products

• 82174-07-0 2-<3-<(trifluoromethyl)thio>phenyl>ethylamine 
• 82173-96-4 C₁₈H₁₉F₆N₃O₄S₄ 
• 82174-09-2 <3-<(trifluoromethyl)thio>phenyl>acetonitrile 
• 215732-90-4 3-<(trifluoromethyl)thio>benzyl chloride 

Relevant academic research and scientific papers

Mild and Soft Catalyzed Trifluoromethylthiolation of Boronic Acids: The Crucial Role of Water

The most reactive 2nd generation of trifluoromethanesulfenamides undergoes a copper-catalyzed cross-coupling reaction with boronic acids to afford CF3S-molecules. Contrary to the previous methods in the literature, no base addition, no heating, and no large excess of reagents are required to obtain good results. Furthermore, a crucial role of a small amount of water to favor this reaction has been demonstrated. This constitutes the mildest described conditions for such a reaction.

N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY

Novel N-hydroxyamide derivatives are disclosed. These N-hydroxyamide derivatives inhibit UPD-3O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase, an enzyme present in gram negative bacteria and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.

Imidodisulfamides. I. A novel class of antagonists of slow-reacting substance of anaphylaxis

A series of N',N''-bis(aryl)- and N',N''-(aralkyl)imidodisulfamides was prepared and evaluated as antagonists of slow-reacting substance of anaphylaxis (SRS-A) induced contractions of isolated guinea pig ileum. Some of these compounds, notably N',N''-bis(4-phenylbutyl)- N',N''-bis[2-(4-chlorophenyl)ethyl]-, and N',N''-bis[2-(4-bromophenyl)ethyl]imidodisulfamides (16, 22, and 26), were moderately potent and selective antagonists of SRS-A. The influence of lipophilic (π) and electronic (σ) factors on SRS-A antagonist activity appears to be of considerable importance to the derivation of potent and selective SRS-A antagonists.