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6H-Pyrazolo[3,4-c]pyridine-3,6-dicarboxylic acid, 1,4,5,7-tetrahydro-, 6-(1,1-dimethylethyl) ester, commonly known as Tofacitinib, is a pharmaceutical compound that functions as a Janus kinase (JAK) inhibitor. It is marketed under the brand name Xeljanz and is utilized in the treatment of various chronic inflammatory conditions by targeting the JAK pathway, which plays a crucial role in the inflammatory response and immune system regulation.

821785-76-6

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821785-76-6 Usage

Uses

Used in Pharmaceutical Industry:
6H-Pyrazolo[3,4-c]pyridine-3,6-dicarboxylic acid, 1,4,5,7-tetrahydro-, 6-(1,1-dimethylethyl) ester is used as a therapeutic agent for the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Its application is based on its ability to inhibit the JAK pathway, which is involved in the inflammatory response and immune system regulation, thereby reducing symptoms and slowing the progression of these chronic inflammatory conditions.
Used in Inflammatory Disease Treatment:
In the treatment of inflammatory diseases, 6H-Pyrazolo[3,4-c]pyridine-3,6-dicarboxylic acid, 1,4,5,7-tetrahydro-, 6-(1,1-dimethylethyl) ester is used as a JAK inhibitor to modulate the immune system and reduce inflammation. Its effectiveness in reducing symptoms and slowing disease progression makes it an important therapeutic option for patients suffering from rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

Check Digit Verification of cas no

The CAS Registry Mumber 821785-76-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,1,7,8 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 821785-76:
(8*8)+(7*2)+(6*1)+(5*7)+(4*8)+(3*5)+(2*7)+(1*6)=186
186 % 10 = 6
So 821785-76-6 is a valid CAS Registry Number.

821785-76-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Boc-1,4,5,7-tetrahydropyrazolo[3,4-c]pyridine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 6-[(2-methylpropan-2-yl)oxycarbonyl]-1,4,5,7-tetrahydropyrazolo[3,4-c]pyridine-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:821785-76-6 SDS

821785-76-6Upstream product

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