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3-Pyridinecarboxylic acid, 4-[(4-bromo-2-fluorophenyl)amino]-1,6-dihydro-1-methyl-6-oxo-, pentafluorophenyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

821791-45-1

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821791-45-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 821791-45-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,1,7,9 and 1 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 821791-45:
(8*8)+(7*2)+(6*1)+(5*7)+(4*9)+(3*1)+(2*4)+(1*5)=171
171 % 10 = 1
So 821791-45-1 is a valid CAS Registry Number.

821791-45-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3,4,5,6-pentafluorophenyl 4-(4-bromo-2-fluoroanilino)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:821791-45-1 SDS

821791-45-1Downstream Products

821791-45-1Relevant academic research and scientific papers

4-Anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase

Spicer, Julie A.,Rewcastle, Gordon W.,Kaufman, Michael D.,Black, Shannon L.,Plummer, Mark S.,Denny, William A.,Quin III, John,Shahripour, Aurash B.,Barrett, Stephen D.,Whitehead, Christopher E.,Milbank, Jared B. J.,Ohren, Jeffrey F.,Gowan, Richard C.,Omer, Charles,Camp, Heidi S.,Esmaeil, Nadia,Moore, Kelley,Sebolt-Leopold, Judith S.,Pryzbranowski, Sally,Merriman, Ronald L.,Ortwine, Daniel F.,Warmus, Joseph S.,Flamme, Cathlin M.,Pavlovsky, Alexander G.,Tecle, Haile

, p. 5090 - 5102 (2008/03/13)

A new series of MEK1 inhibitors, the 4-anilino-5-carboxamido-2-pyridones, were designed and synthesized using a combination of medicinal chemistry, computational chemistry, and structural elucidation. The effect of variation in the carboxamide side chain,

5-SUBSTITUTED-4-`(SUBSTITUTED PHENYL)!AMINO!-2-PYRIDONE DEVIATIVES FOR USE AS MEK INHIBITORS

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Page 78, (2010/02/10)

The present invention relates to 5-substituted-4-(substituted) phenylamino-2-pyridone derivatives of formula (I), pharmaceutical compositions and methods of use thereof as MEK inhibitors. Formula (I) wherein W is formula (II), formula (III), formula (IV),

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