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2,3,4,6-tetra-O-acetyl-N,N-bis(2-chloroethyl)-L-glucopyranosylamine is a synthetic chemical compound that belongs to the class of nitrogen mustard drugs. It is a derivative of the natural sugar glucose, featuring two chloroethyl groups known for their alkylating properties. 2,3,4,6-tetra-O-acetyl-N,N-bis(2-chloroethyl)-L-glucopyranosylamine is acetylated at four positions, making it a potent DNA cross-linking agent that causes DNA damage and inhibits cell proliferation. Its cytotoxic effects make it a valuable chemotherapeutic agent.

82198-59-2

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82198-59-2 Usage

Uses

Used in Cancer Treatment:
2,3,4,6-tetra-O-acetyl-N,N-bis(2-chloroethyl)-L-glucopyranosylamine is used as a chemotherapeutic agent for the treatment of certain lymphomas and leukemias. Its alkylating properties allow it to cross-link DNA, leading to DNA damage and the inhibition of cell proliferation, which is crucial in controlling the growth of cancer cells.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3,4,6-tetra-O-acetyl-N,N-bis(2-chloroethyl)-L-glucopyranosylamine is used as a research compound for the development of new cancer therapies. Its unique structure and DNA cross-linking capabilities make it a promising candidate for the study and design of novel anticancer drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 82198-59-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,1,9 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 82198-59:
(7*8)+(6*2)+(5*1)+(4*9)+(3*8)+(2*5)+(1*9)=152
152 % 10 = 2
So 82198-59-2 is a valid CAS Registry Number.

82198-59-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name L-Glucopyranosylamine, N,N-bis(2-chloroethyl)-, 2,3,4,6-tetracetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82198-59-2 SDS

82198-59-2Upstream product

82198-59-2Downstream Products

82198-59-2Relevant academic research and scientific papers

Synthesis and biological activity of nitrogen mustards carbohydrate derivatives

Moruzzi,Montero,Imbach

, p. 125 - 132 (2007/10/02)

The authors describe the synthesis of N,N-bis(2-chloroethyl) amine carbohydrate derivatives, using sugar moieties previously associated with other oncostatic agents. The structure of these compounds was determined using 1H and 13C NMR spectroscopy. Their antitumor activity on L1210 on mice and their immunodepressive effects have been evaluated.

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