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Usage

Uses

Used in Pharmaceutical Industry:
Isothiazole-4-carbaldehyde is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicine.
Used in Agrochemical Industry:
In the agrochemical sector, Isothiazole-4-carbaldehyde is employed as an intermediate for the production of agrochemicals. Its reactivity and chemical properties make it suitable for the creation of compounds used in agricultural applications to improve crop protection and yield.
Used in Dye Production:
Isothiazole-4-carbaldehyde is used as a starting material in the production of dyes. Its chemical structure provides a foundation for creating a variety of dyes with different color properties, used in textiles and other industries.
Used in Flavor and Fragrance Industry:
Isothiazole-4-carbaldehyde is also used as an intermediate in the creation of flavors and fragrances. Its pungent odor and chemical versatility make it a valuable ingredient in the formulation of various scented products.
Used in Organic Synthesis:
Isothiazole-4-carbaldehyde is a versatile building block in organic synthesis, with potential applications in the development of new organic compounds for a range of uses across the chemical industry. Its unique properties allow for the creation of diverse products, enhancing the capabilities of chemical research and development.

Upstream product

• 1104606-20-3 N-methoxy-N-methyl-isothiazole-4-carboxamide 
• 170283-02-0 4-hydroxymethylisothiazole 
• 68-12-2 N,N-dimethyl-formamide 
• 49602-28-0 4-iodoisothiazole 
• 30192-61-1 1-(isothiazole-4-carbonyl)-1,2-dihydro-quinoline-2-carbonitrile 

Relevant academic research and scientific papers

A convenient regiospecific synthesis of isothiazol-4-yl derivatives

Synthesis of derivatives resulting from the formation of a carbon-carbon bond in 4-position of the isothiazole is easily obtained by using the 4-magnesioisothiazole prepared via metal halogen exchange.

RESORCINOL N-ARYL AMIDE COMPOUNDS, FOR USE AS PYRUVATE DEHYDROGENASE KINASE INHIBITORS

A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: Y is –CONR1- or optionally substituted arylene or optionally substituted heteroarylene; R1 is H, Cl, F, CH3 or CF3; 10 each R4 is independently H, CH3 or F; R5 is H or CH3; and each R2 and R6 is independently (Alk)n-Rn-(Alk)n-Rn-(Alk)n-X; The compounds of the invention are useful as resorcinol N-aryl amide (NAA) compounds, which are suitable for use as PDK inhibitors, for example for 15 inhibition of cancer cell proliferation.

TRIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS

Beta-carboline derivatives of structural formula (I) are selective antagonists of the somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.

BENZAZEPIN-2(1H)-ONE DERIVATIVES

Compounds of formula (I) and pharmaceutically acceptable salts thereof are agonists at the beta-2 adrenoceptor. They are useful as feed additives for livestock animals.