822-54-8

Basic information

• Product Name: Isothiazole-4-carbaldehyde
• Synonyms: Isothiazole-4-carbaldehyde
• CAS NO: 822-54-8
• Molecular Formula: C₄H₃NOS
• Molecular Weight: 113.13772
• Mol File: 822-54-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 98.454 °C at 760 mmHg
• Flash Point: 13.345 °C
• Appearance: /
• Density: 1.35 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Isothiazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: Isothiazole-4-carbaldehyde(822-54-8)
• EPA Substance Registry System: Isothiazole-4-carbaldehyde(822-54-8)

Safety Data

• Hazardous Substances Data: 822-54-8(Hazardous Substances Data)

Usage

General Description

Isothiazole-4-carbaldehyde is a chemical compound with the molecular formula C4H3NOS. It is a yellowish liquid with a pungent odor, and is mainly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also utilized in the production of dyes, flavors, and fragrances. Its structure contains a heterocyclic ring with a sulfur atom, which gives it unique chemical properties and reactivity. Isothiazole-4-carbaldehyde is a versatile building block in organic synthesis and has various potential applications in the fields of medicine, agriculture, and the chemical industry. Due to its synthesis and potential versatile applications, it is a valuable chemical compound in the field of organic chemistry.

Upstream product

• 1104606-20-3 N-methoxy-N-methyl-isothiazole-4-carboxamide 
• 170283-02-0 4-hydroxymethylisothiazole 
• 30192-61-1 1-(isothiazole-4-carbonyl)-1,2-dihydro-quinoline-2-carbonitrile 
• 68-12-2 N,N-dimethyl-formamide 
• 49602-28-0 4-iodoisothiazole 

Relevant articles and documents

A convenient regiospecific synthesis of isothiazol-4-yl derivatives

Synthesis of derivatives resulting from the formation of a carbon-carbon bond in 4-position of the isothiazole is easily obtained by using the 4-magnesioisothiazole prepared via metal halogen exchange.

TRIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS

Beta-carboline derivatives of structural formula (I) are selective antagonists of the somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.

Isothiazolecarboxaldoximes and methylated derivatives as therapeutic agents in poisoning by organophosphorus compounds.

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