82211-92-5

Basic information

• Product Name: 4-(2-CHLORO-PHENYL)-PIPERIDINE HYDROCHLORIDE
• Synonyms: 4-(2-CHLOROPHENYL)PIPERIDINE HCL;4-(2-CHLORO-PHENYL)-PIPERIDINE HYDROCHLORIDE
• CAS NO: 82211-92-5
• Molecular Formula: C₁₁H₁₄ClN*ClH
• Molecular Weight: 232.15
• Mol File: 82211-92-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 311.4°C at 760 mmHg
• Flash Point: 142.2°C
• Appearance: /
• Vapor Pressure: 0.000416mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(2-CHLORO-PHENYL)-PIPERIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-CHLORO-PHENYL)-PIPERIDINE HYDROCHLORIDE(82211-92-5)
• EPA Substance Registry System: 4-(2-CHLORO-PHENYL)-PIPERIDINE HYDROCHLORIDE(82211-92-5)

Safety Data

• Hazardous Substances Data: 82211-92-5(Hazardous Substances Data)

Usage

General Description

4-(2-chloro-phenyl)-piperidine hydrochloride is a chemical compound that is commonly used in the synthesis of pharmaceutical drugs. It is a piperidine derivative with a chloro-substituted phenyl group, and the hydrochloride salt form is often utilized for its increased solubility and stability. This chemical has been studied for its potential applications in treating various medical conditions, including neurological and psychiatric disorders. Additionally, it may also be used as a building block in the development of new medications and research compounds. The compound's properties and structure make it a valuable tool in the pharmaceutical industry for drug discovery and development.

InChI:InChI=1/C11H14ClN.ClH/c12-11-4-2-1-3-10(11)9-5-7-13-8-6-9;/h1-4,9,13H,5-8H2;1H

Upstream product

• 1274934-00-7 1-[4-(2-chloro-phenyl)-piperidin-1-yl]-ethanone 
• 1274933-99-1 1-[4-(2-amino-phenyl)-piperidin-1-yl]-ethanone 
• 1274933-98-0 1-[4-(2-nitro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]ethanone 
• 1274933-97-9 4-(2-nitro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride 
• 494795-55-0 tert-butyl 4-(2-nitrophenyl)-5,6-dihydropyridine-1(2H)-carboxylate 

Relevant articles and documents

(4-PHENYL-PIPERIDIN-1-YL)-[5-1H-PYRAZOL-4YL)-THIOPHEN-3-YL]-METHANONE COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain (4-phenyl-piperidin-1-yl)- [5-(1 H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds that, inter alia, inhibit 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD1 ). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit 1 1 β-hydroxysteroid dehydrogenase type 1; to treat disorders that are ameliorated by the inhibition of 11 β-hydroxysteroid dehydrogenase type 1; to treat the metabolic syndrome, which includes disorders such as type 2 diabetes and obesity, and associated disorders including insulin resistance, hypertension, lipid disorders and cardiovascular disorders such as ischaemic (coronary) heart disease; to treat CNS disorders such as mild cognitive impairment and early dementia, including Alzheimer's disease; etc.