82215-18-7

Basic information

• Product Name: benzyl 2-{[(benzyloxy)carbonyl]amino}-3-cyanopropanoate
• CAS NO: 82215-18-7
• Molecular Formula: C₁₉H₁₈N₂O₄
• Molecular Weight: 338.3572
• Mol File: 82215-18-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 561.1°C at 760 mmHg
• Flash Point: 293.1°C
• Density: 1.23g/cm³
• Vapor Pressure: 1.28E-12mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: benzyl 2-{[(benzyloxy)carbonyl]amino}-3-cyanopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-{[(benzyloxy)carbonyl]amino}-3-cyanopropanoate(82215-18-7)
• EPA Substance Registry System: benzyl 2-{[(benzyloxy)carbonyl]amino}-3-cyanopropanoate(82215-18-7)

Safety Data

• Hazardous Substances Data: 82215-18-7(Hazardous Substances Data)

Upstream product

• 4668-39-7 benzyl N^α-benzyloxycarbonyl-L-asparaginate 
• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 
• 100-51-6 benzyl alcohol 
• 14985-43-4 N-benzoyl-2',3'-di-O-benzoyladenosine 
• 82215-19-8 Cbz-thioasparaginyl benzyl ester 

Relevant articles and documents

An improved synthesis of β-cyano- l -alanine esters and amides

We have developed a novel, mild, efficient, and scalable protocol for the synthesis of N-protected β-cyano-l-alanine esters or -amides from N-protected l-asparagin. This protocol avoided the use of toxic or unpleasant reagents and was easy to operate in laboratory.

AMINO ACID SURROGATES : AN INDIRECT METHOD FOR THE SYNTHESIS OF PEPTIDES CONTAINING THE THIOASPARAGINYL RESIDUE

The protected pentapeptide, Boc-Tan-Cys(PMB)-Pro-Leu-GlyNH2 and related thioasparaginyl compounds were prepared by an indirect method from their corresponding β-cyanoalanyl precursors by treatment with H2S/NH3.The optical purities of thioasparagine (Tan)