82244-36-8Relevant academic research and scientific papers
General and direct synthesis of 3-aminoindolizines and their analogues via Pd/Cu-catalyzed sequential cross-coupling/cycloisomerization reactions
Liu, Yuanhong,Song, Zhiquan,Yan, Bin
, p. 409 - 412 (2007)
An efficient and one-step synthesis of 3-aminoindolizines or benz[e]indolizines from the reactions of propargyl amines or amides with heteroaryl bromides was developed. This methodology is realized by a tandem reaction using Pd/Cu catalysts, which could c
Synthesis of 3-(Dialkylamino)indolizines. Reaction of 3-(2-Pyridyl)-2-propenals with Secondary Amines
Abe, Yoshihito,Ohsawa, Akio,Igeta, Hiroshi
, p. 881 - 886 (2007/10/02)
Reaction of 2- or 3-substituted 3-(2-pyridyl)-propenals (3a-f) with secondary amines afforded 2- or 1-substituted 3-(dialkylamino)indolizines (2a-l) in the presence of metal halides.It was found that titanium tetrachloride was the best catalyst.
