82258-37-5

Usage

Uses

Used in Organic Synthesis:
ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE is used as a key intermediate in the synthesis of various organic compounds for different industries. Its unique structure allows it to participate in a range of chemical reactions, facilitating the creation of new molecules with specific properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE is utilized as a building block for the development of new drugs. Its versatility in chemical reactions enables the synthesis of complex molecules with potential therapeutic effects.
Used in Agrochemical Industry:
ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE is also employed in the agrochemical industry, where it serves as a precursor for the synthesis of various agrochemical products, such as pesticides and herbicides, contributing to the development of more effective and environmentally friendly solutions for agricultural practices.
Used in Chemical Research:
In the field of chemical research, ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE is used as a model or reference in studies aimed at understanding the properties and behavior of similar organic compounds. Its reactivity and structural features make it a valuable tool for advancing scientific knowledge in organic chemistry.

Upstream product

• 110-89-4 piperidine 
• 50-00-0 formaldehyd 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 37136-99-5 1-((6-bromohexyl)oxy)-4-chlorobenzene 

Downstream Products

• 124083-19-8 (R)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carboxylic acid methyl ester 
• 124083-24-5 (S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carboxylic acid methyl ester 
• 124083-14-3 etomoxir 
• 124083-22-3 (S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carboxylic acid 
• 124151-59-3 {2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol 
• 124083-21-2 (R)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carbaldehyde 
• 124083-16-5 8-(4-Chloro-phenoxy)-2-methylene-octanoyl chloride 
• 124083-23-4 {(R)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol 
• 124083-18-7 {(S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol 
• 7170-57-2 7-(4-chlorophenoxy)heptanoic acid 
• 314263-47-3 (R)-8-(4-Chloro-phenoxy)-2-hydroxy-2-methanesulfonyloxymethyl-octanoic acid ethyl ester 
• 314263-46-2 (S)-2-Acetoxymethyl-8-(4-chloro-phenoxy)-2-hydroxy-octanoic acid ethyl ester 
• 314263-48-4 ethyl (R)-2,3-dihydroxy-2-[6-(p-chlorophenoxy)hexyl]propanoate 
• 124083-20-1 (R)-(+)-etomoxir 

Relevant academic research and scientific papers

The Baylis-Hillman chemistry in aqueous media: A convenient synthesis of 2-methylenealkanoates and alkanenitriles

A convenient, general and efficient synthesis of 2-methylenealkanoates and alkanenitriles is accomplished via the regioselective nucleophilic (SN2′) addition of hydride ion from NaBH4 to (2Z)-2-(bromomethyl)alk-2-enoates and 2-(bromomethyl)alk-2-enenitriles respectively in the presence of DABCO in environment friendly aqueous media. Synthesis of two hypoglycemic agents is also described.

Asymmetric synthesis of (R)-(+)-etomoxir via enzymatic resolution

An asymmetric synthesis of (R)-(+)-etomoxir 3, employing enzymatic resolution of ethyl 2-alkyl-2,3-dihydroxypropionate using Amano AK via transacylation is reported. Copyright (C) 2000 Elsevier Science Ltd.

Phospholipase A2 inhibitors

There is disclosed a method for the treatment of immunoinflammatory conditions, such as allergy, anaphylaxis, asthma and inflammation in mammals which comprises administering to a mammal so afflicated an effective amount of a compound having the formula:

Phospholipase A2 inhibitors

There is disclosed a method for the treatment of immunoinflammatory conditions, such as allergy, anaphylaxis, asthma and inflammation in mammals which comprises administering to a mammal so afflicted an effective amount of a compound having the formula: S

Phenalkoxyalkyl- and phenoxyalkyl-substituted oxiranecarboxylic acids, their use and medicaments containing them

Phenalkoxyalky- and phenoxyalkyl-substituted oxiranecarboxylic acids of the formula STR1 wherein R1 denotes a hydrogen atom (--H), a halogen atom, a lower alkyl group, a lower alkoxy group, a nitro group or a trifluoromethyl group, R2 has one of the meanings of R1, R3 denotes a hydrogen atom (--H) or a lower alkyl group, Y denotes --O--(CH2)m --, m denotes O or an integer from 1 to 4, and n denotes an integer from 2 to 8, with the proviso that the sum of m and n is an integer from 2 to 8, and the salts of the acids are new compounds. They display a hypoglycaemic action in warm-blooded animals. Processes for the preparation of the new compounds and of the intermediate products required for their preparation are described.