82258-37-5

Basic information

• Product Name: ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE
• Synonyms: ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE;8-(4-Chlorophenoxy)-2-Methylene-octanoic Acid Ethyl Ester
• CAS NO: 82258-37-5
• Molecular Formula: C₁₇H₂₃ClO₃
• Molecular Weight: 310.82
• Product Categories: Aromatics Compounds;Aromatics;Intermediates
• Mol File: 82258-37-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Solubility: Acetone, Ethyl Acetate, Methanol
• CAS DataBase Reference: ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE(82258-37-5)
• EPA Substance Registry System: ETHYL 8-(4-CHLOROPHENOXY)-2-METHYLEN-OCTANOATE(82258-37-5)

Safety Data

• Hazardous Substances Data: 82258-37-5(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

Ethyl 8-(4-Chlorophenoxy)-2-methylen-octanoate (cas# 82258-37-5) is a compound useful in organic synthesis.

Upstream product

• 110-89-4 piperidine 
• 50-00-0 formaldehyd 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 37136-99-5 1-((6-bromohexyl)oxy)-4-chlorobenzene 

Downstream Products

• 82258-36-4 2-(6-(4-chlorophenoxy)-hexyl)-oxirane-2-carboxylic acid ethyl ester 
• 201598-02-9 ethyl 2,3-dihydroxy-2-[6-(p-chlorophenoxy)hexyl]propanoate 
• 124083-19-8 (R)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carboxylic acid methyl ester 
• 124083-24-5 (S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carboxylic acid methyl ester 
• 124083-14-3 etomoxir 
• 124083-22-3 (S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carboxylic acid 
• 124151-59-3 {2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol 
• 124083-21-2 (R)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxirane-2-carbaldehyde 
• 124083-16-5 8-(4-Chloro-phenoxy)-2-methylene-octanoyl chloride 
• 124083-23-4 {(R)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol 
• 124083-18-7 {(S)-2-[6-(4-Chloro-phenoxy)-hexyl]-oxiranyl}-methanol 
• 7170-57-2 7-(4-chlorophenoxy)heptanoic acid 
• 314263-47-3 (R)-8-(4-Chloro-phenoxy)-2-hydroxy-2-methanesulfonyloxymethyl-octanoic acid ethyl ester 
• 314263-46-2 (S)-2-Acetoxymethyl-8-(4-chloro-phenoxy)-2-hydroxy-octanoic acid ethyl ester 

Relevant articles and documents

The Baylis-Hillman chemistry in aqueous media: A convenient synthesis of 2-methylenealkanoates and alkanenitriles

A convenient, general and efficient synthesis of 2-methylenealkanoates and alkanenitriles is accomplished via the regioselective nucleophilic (SN2′) addition of hydride ion from NaBH4 to (2Z)-2-(bromomethyl)alk-2-enoates and 2-(bromomethyl)alk-2-enenitriles respectively in the presence of DABCO in environment friendly aqueous media. Synthesis of two hypoglycemic agents is also described.

Phospholipase A2 inhibitors

There is disclosed a method for the treatment of immunoinflammatory conditions, such as allergy, anaphylaxis, asthma and inflammation in mammals which comprises administering to a mammal so afflicated an effective amount of a compound having the formula:

Phenalkoxyalkyl- and phenoxyalkyl-substituted oxiranecarboxylic acids, their use and medicaments containing them

Phenalkoxyalky- and phenoxyalkyl-substituted oxiranecarboxylic acids of the formula STR1 wherein R1 denotes a hydrogen atom (--H), a halogen atom, a lower alkyl group, a lower alkoxy group, a nitro group or a trifluoromethyl group, R2 has one of the meanings of R1, R3 denotes a hydrogen atom (--H) or a lower alkyl group, Y denotes --O--(CH2)m --, m denotes O or an integer from 1 to 4, and n denotes an integer from 2 to 8, with the proviso that the sum of m and n is an integer from 2 to 8, and the salts of the acids are new compounds. They display a hypoglycaemic action in warm-blooded animals. Processes for the preparation of the new compounds and of the intermediate products required for their preparation are described.