82262-31-5

Upstream product

• 814-78-8 3-Methyl-3-buten-2-one 
• 18424-77-6 sodium diethyl methylmalonate 
• 615-89-4 2,4-dimethyl-5-hydroxyphenol 
• 141-97-9 ethyl acetoacetate 
• 80-62-6 methacrylic acid methyl ester 
• 93176-58-0 3-Methyl-5-methoxycarbonylhexan-2-one 
• 97-63-2 methyl methacrylate 
• 93176-86-4 3-Ethoxycarbonyl-5-methoxycarbonyl-3-methylhexan-2-one 
• 78-93-3 butanone 
• 2323-28-6 2,4-dimethyl-5-ketohexanoic acid 
• 74650-83-2 methyl α-methyl-γ-carboethoxy-γ-acetylbutyrate 
• 585-07-9 tert-Butyl methacrylate 

Downstream Products

• 3891-70-1 meso-2,4-dimethylpentane-1,5-diol 
• 3891-69-8 DL-2,4-dimethylglutaric acid 
• 85951-44-6 2,2'Methylenbis(4,6-dimethyl-1,3-cyclohexandion) 
• 60068-01-1 3-isobutoxy-4,6-dimethyl-2-cyclohexen-1-one 
• 69841-15-2 meso-4,6-dimethylcyclohexane-1,3-dione 
• 104355-62-6 4,4,6-trimethylcyclohexane-1,3-dione 
• 82262-20-2 4,6-dimethyl-4-<2-(tetrahydro-2H-pyran-2-yloxy)ethyl>-2-cyclohexen-1-one 
• 82262-19-9 3-Isobutoxy-4,6-dimethyl-6-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclohex-2-enol 
• 82262-18-8 3-isobutoxy-4,6-dimethyl-6-<2-(tetrahydro-2H-pyran-2-yloxy)ethyl>-2-cyclohexen-1-one 
• 101100-42-9 2,4-dimethyl-7-phenyl-heptanoic acid 
• 13789-55-4 5-Phenylsulfonyl-4-<β-benzolsulfonyl-hydrazino>-1,3-dimethyl-cyclohexen-(4)-on-(6) 
• 93198-26-6 2-m-Methoxyphenyliminmomethyl-4,6-dimethylcyclohexane-1,3-dione 
• 13789-51-0 1,3-Dimethyl-4-benzolsulfonylhydrazino-6-oxo-cyclohexen-⁽⁴⁾ 
• 101870-50-2 2-benzyl-4,6-dimethyl-cyclohexane-1,3-dione 

Relevant academic research and scientific papers

TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF

The present disclosure provides compounds of Formula (I), and salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be useful for inhibiting kinases

SUBSTITUTED TETRAHYDROQUINOLINONE COMPOUNDS AS ROR GAMMA MODULATORS

The present invention provides substituted tetrahydroquinolinone and related compounds of formula (I), which are therapeutically useful as modulators of Retinoic acid receptor-related orphan receptors (RORs), more particularly as RORγ modulators. These co

Heterocyclic Steroids: Part IV - Synthesis of (+/-)-3-Methoxy-11α-methyl-6,15-diazaestra-1,3,5,7,9,14-hexaene and Some Related Hydrophenanthridinones

3-Methoxy-8,10-dimethyl-9,10-dihydrophenanthridin-7(8H)-one (III), readily available from 4,6-dimethylcyclohexane-1,3-dione (I), m-anisidine and ethyl orthoformate is condensed with ethyl acrylate to give the adduct (V).The derived acid azide (VII) is submitted to a modified Curtius rearrangement to furnish (+/-)-3-methoxy-11α-6,15-diazaestra-1,3,5,7,9,14-hexaene (VIII), a steroid containing in its framework an 11-methyl group, a quinoline ring and an indole moiety.In another experiment the isoxazole (X) derived from 3-methoxy-10α-methyl-9,10-dihydrophenanthridin-7(8H)-one (IX) is alkylated with methyl iodide and potassium t-butoxide and three products (XI), (XII) and (XIII) methylated to different degree and at different positions have been isolated.The relative configuration and conformation of the hydrophenanthridinones are established from PMR.