82272-29-5Relevant academic research and scientific papers
Cyanomethyl anion transfer reagents for diastereoselective Corey-Chaykovsky cyclopropanation reactions
Hommelsheim, Renè,Hock, Katharina J.,Schumacher, Christian,Hussein, Mohanad A.,Nguyen, Thanh V.,Koenigs, Rene M.
supporting information, p. 11439 - 11442 (2018/10/20)
A readily available and bench-stable cyanomethyl sulfonium salt was used in highly diastereoselective Corey-Chaykovsky cyclopropanation reactions of electron-poor olefins. This efficient method provides a rapid route to access densely functionalized cyclopropyl nitriles.
The formation of cyclopropane derivatives bearing 1,2-dicarbonyl groups through tandem Michael-Favorskii-type reactions with (E) -β-styrylselenonium triflate
Watanabe, Shin-Ichi,Nakayama, Ippei,Kataoka, Tadashi
, p. 1493 - 1496 (2007/10/03)
A novel tandem Michael-Favorskii-type reaction is described. Treatment of active methylene carbanions, prepared by the reaction of NaH and active methylene compounds, with (E)-β-styrylselenonium triflate in DMF at 70°C for 3 h gave cyclopropane derivatives bearing 1,2-dicarbonyl groups in moderate to good yields. On the other hand, the carbanions derived from malonates reacted with the selenonium salt to afford 1,1-dicarbonylcyclopropane compounds in good yields. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.
