82275-89-6Relevant academic research and scientific papers
A new method for the preparation of nitrogen-containingheterocycles using diphenylsulfonium triflates
Yamanaka, Hiroyuki,Yamane, Yoshinobu,Mukaiyama, Teruaki
, p. 2813 - 2826 (2007/10/03)
Various nitrogen heterocycles were produced by the reactions of ω-bromoalkyldiphenylsulfonium or diphenylsyylsulfonium triflates with nitrogen nucleophiles. Further, the reactions of diphenylstyrylsulfonium triflates with N-metalated phthalimide and imida
RING-CLOSURE REACTIONS. XX. AN EFFICIENT SYNTHESIS OF MANY-MEMBERED AZACYCLOALKANES
Gargano, Patrizia,Mandolini, Luigi
, p. 31 - 34 (2007/10/02)
An efficient cyclization of N-tosyl-ω-bromoalkylamines to N-tosylazacycloalkanes in the presence of a combination of EtOK/K2CO3 in Me2SO solution is described.This base-solvent system permitted the high-dilution conditions favourable to cyclization to be attained with a conveniently high rate of feed of the bifunctional reactants into the reaction medium.Yields are very good for the large rings, and still satisfactory, although significantly lower, for the medium-sized rings.
