82297-05-0Relevant articles and documents
PALLADIUM-PROMOTED ASYMMETRIC OXYAMINATION OF ALKENES APPLICATION TO THE SYNTHESIS OF OPTICALLY ACTIVE ARYLOXYPROPANOLAMINES
Baeckvall, Jan-E.,Bjoerkman, Eva E.,Bystroem, Styrbjoern E.
, p. 943 - 946 (2007/10/02)
Palladium-promoted oxyamination of some alkenes using optically active N-methyl-α-phenylethylamine as amine nucleophile, or using optically active N,N-dimethyl-α-phenylethylamine as ligand, produces optically active aminoalcoholderivatives in an optical yield of 3-60percent.Oxyamination of aryl allyl ethers gives optically active 1-amino-3-aryloxy-propan-2-ol derivatives, which are important β-blockers.