82299-33-0

Basic information

• Product Name: 3-ethoxy-λ⁶-thietane 1,1-dioxide
• Synonyms: 3-ethoxy-λ⁶-thietane 1,1-dioxide
• CAS NO: 82299-33-0
• Molecular Weight: 150.199
• Mol File: 82299-33-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-ethoxy-λ⁶-thietane 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethoxy-λ⁶-thietane 1,1-dioxide(82299-33-0)
• EPA Substance Registry System: 3-ethoxy-λ⁶-thietane 1,1-dioxide(82299-33-0)

Safety Data

• Hazardous Substances Data: 82299-33-0(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1425223-00-2 3-bromo-1-(1,1-dioxothietan-3-yl)-5-phenoxy-1H-1,2,4-triazole 
• 208577-20-2 8-bromo-1,3-dimethyl-7-(1,1-dioxothietan-3-yl)-3,7-dihydro-1H-pyrine-2,6-dione 
• 159326-43-9 2-chloro-1-<3-(1,1-dioxythietanyl)>benzimidazole 
• 1181206-90-5 5-benzylamino-3-bromo-1-(1,1-dioxo-λ⁶-thietan-3-yl)-1H-1,2,4-triazole 

Relevant articles and documents

Thietanyl Protection in the Synthesis of 5-Aryloxy(sulfonyl)-3-bromo-1,2,4-triazoles

Previously unknown 5-aryloxy- and 5-benzenesulfonyl-3-bromo-1H-1,2,4-triazoles have been synthesized starting from 3,5-dibromo-1,2,4-triazole by successive alkylation with 2-chloromethylthiirane, nucleophilic substitution of the 5-bromine atom by phenoxy

Thietane ring as a novel protecting group

A novel protecting group for NH functionality of heterocycles, a thietane ring, was proposed. It can be readily introduced by alkylation of NH-heterocycles with 2-chloromethylthiirane. Removal of the thietane protecting group is performed via oxidation to thietane 1,1-dioxide with hydrogen peroxide in acetic acid and subsequent treatment with sodium alkoxide.