82326-46-3 Usage
Structure
Benzene ring fused to an imidazole ring, with a phenoxy group and a methyl group attached to the benzimidazole ring
Classification
Benzimidazole derivative
Usage
Potential drug candidate in medicinal chemistry and pharmaceuticals
Biological activities
Antimicrobial, antiviral, and anticancer properties
Potential applications
Anti-inflammatory, analgesic, and anticonvulsant agents.
Check Digit Verification of cas no
The CAS Registry Mumber 82326-46-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,2 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 82326-46:
(7*8)+(6*2)+(5*3)+(4*2)+(3*6)+(2*4)+(1*6)=123
123 % 10 = 3
So 82326-46-3 is a valid CAS Registry Number.
82326-46-3Relevant academic research and scientific papers
Inhibition of Rat Hepatic Microsomal Aminopyrine N-Demethylase Activity by Benzimidazole Derivatives. Quantitative Structure-Activity Relationships
Murray, Michael,Ryan, Adrian J.,Little, Peter J.
, p. 887 - 892 (2007/10/02)
Eighty-two benzimidazole derivatives have been prepared and tested for the ability to inhibit cytochrome P-450 mediated enzyme activity (aminopyrine N-demethylase) from phenobarbitone-induced rat hepatic microsomes.Using physicochemical parameters and multiple regression analysis, we derived a quantitative structure-activity relationship (QSAR) that describes up to 87percent of the data variance in terms of hydrophobic and electronic effects and the molar refractivity of the substituent in the 2-position of the benzimidazole ring.
