82336-05-8Relevant academic research and scientific papers
A Short and Stereoselective Synthesis of the Carbapenem Antibiotic PS-5
Kametani, Tetsuji,Honda, Toshio,Nakayama, Atsushi,Sasakai, Yuko,Mochizuki, Tomoko,Fukumoto, Keiichiro
, p. 2228 - 2232 (1981)
The benzyl ester (3) and p-nitrobenzyl ester (PNB ester) (4) of the antibiotic PS-5 and the bis-protected PS-6 (5) were stereoselectively synthesised by application of the new carbon-carbon bond formation reaction at the C-4-position of 4-acetoxy-3-ethyl-
FACILE SYNTHESIS OF CARBAPENEM ANTIBIOTICS. THE FIRST AND SIMPLE STEREOSELECTIVE SYNTHESIS OF ANTIBIOTIC PS-5 BENZYL ESTER
Kametani, Tetsuji,Honda, Toshio,Nakayama, Atsushi,Fukumoto, Keiichiro
, p. 1967 - 1971 (2007/10/02)
Antbiotic PS-5 benzyl ester was stereoselectively synthesized by using a new carbon-carbon bond formation reaction at the C4-position of azeticin-2-one, as a key reaction.
