82355-83-7Relevant academic research and scientific papers
ORGANOMETALLIC INDUCED SELF-CONDENSATION OF CARBOXAMIDES
Babudri, F.,Ciminale, F.,Nunno, L. Di,Florio, S.
, p. 557 - 561 (2007/10/02)
N,N-Disubstituted carboxamides containing α-hydrogen atoms undergo self-condensation reaction simply on treatment with Grignard reagents or n-BuLi in THF at room temp.The reaction is considerably influenced by steric hindrance at the α-carbon and the condensing agent utilized.A possible Claisen-type mechanism is also reported.
