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1,3-Dibutyl-1,1,3,3-tetramethyldisilazane, with the molecular formula C14H36N2Si2, is a clear, colorless liquid chemical compound. It is widely recognized for its role as a reagent in organic synthesis, particularly as a silylation agent. Its unique ability to protect hydroxyl, amino, and carboxylic acid groups from unwanted reactions makes it an indispensable tool in organic chemistry research. Furthermore, it serves as a precursor in the synthesis of silicone polymers and finds use as a sealant in various applications, showcasing its versatility and broad utility across different industries.

82356-80-7

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82356-80-7 Usage

Uses

Used in Organic Synthesis:
1,3-Dibutyl-1,1,3,3-tetramethyldisilazane is used as a silylation reagent for the derivatization of polar functional groups in organic synthesis. Its application is crucial for protecting sensitive functional groups from unwanted side reactions, thereby facilitating cleaner and more controlled synthetic pathways.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,3-Dibutyl-1,1,3,3-tetramethyldisilazane is utilized as a protecting agent for active pharmaceutical ingredients. It helps in the selective derivatization of functional groups, which is essential for the development of new drugs and the improvement of existing drug formulations.
Used in Chemical Research:
1,3-Dibutyl-1,1,3,3-tetramethyldisilazane is employed as a research tool in chemical laboratories. It aids scientists in studying the reactivity and properties of various functional groups, contributing to the advancement of chemical knowledge and the discovery of novel chemical reactions.
Used in Silicone Polymer Production:
As a precursor in the production of silicone polymers, 1,3-Dibutyl-1,1,3,3-tetramethyldisilazane plays a vital role in the synthesis of materials with unique properties such as heat resistance, flexibility, and biocompatibility. These polymers find applications in various industries, including electronics, medical devices, and automotive components.
Used in Sealant Formulations:
1,3-Dibutyl-1,1,3,3-tetramethyldisilazane is used as a component in sealant formulations, providing excellent adhesion and sealing properties. Its use in this application is particularly beneficial in industries where high-performance sealing solutions are required, such as construction, automotive, and aerospace.

Check Digit Verification of cas no

The CAS Registry Mumber 82356-80-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,5 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 82356-80:
(7*8)+(6*2)+(5*3)+(4*5)+(3*6)+(2*8)+(1*0)=137
137 % 10 = 7
So 82356-80-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H31NSi2/c1-7-9-11-14(3,4)13-15(5,6)12-10-8-2/h13H,7-12H2,1-6H3

82356-80-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[[[butyl(dimethyl)silyl]amino]-dimethylsilyl]butane

1.2 Other means of identification

Product number -
Other names Silanamine,1-butyl-N-(butyldimethylsilyl)-1,1-dimethyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82356-80-7 SDS

82356-80-7Downstream Products

82356-80-7Relevant academic research and scientific papers

Synthesis and characterization of dibutyltetramethyldisilazane-bonded silica phases for reversed-phase high-performance liquid chromatography

Zhang, Renen,Xie, Zemin,Zhao, Rui,Li, Xiaohua,Liu, Guoquan,Aguilar, Marie-Isabel,Hearn, Milton T. W.

, p. 1861 - 1867 (1991)

A new silane, di-n-butyltetramethyldisilazane (DBTMDS), has been synthesized. Silanizations withh DBTMDS of a narrow-pore and a wide-pore silica yielded relatively high concentrations of bonded n-butyl ligands, of 4.22 and 4.09 μmol/m2, respectively. The chromatographic properties of the n-butyl bonded phase (C4-NH), synthesized with DBTMDS, were compared with n-butyl bonded phases (C4-CL) synthesized with n-butyldimethylchlorosilane (BDMCS) and Vydac-C4 under the same chromatographic conditions. The adsorption of basic compounds including N,N-diethylaniline (N,N-DEA), dansylarginine (Dns-Arg), and (phenyithio)hydantoin-arginine (PTH-Arg), as well as several polypeptides and small proteins including angiotensin I, angiotensin II, and lysozyme, was shown to be less for the C4-NH sorbents than for C4-CL and Vydac-C4 sorbents. While the S value for the basic protein lysozyme was significantly lower on the wide-pore C4-NH sorbent, the S and log k0 values for a range of selected proteins were comparable to those obtained with the Vydac-C4 sorbent. The tests of hydrolytic stability of the bonded phases showed significantly greater stability for the C4-NH sorbents than for the C4-CL sorbents under isocratic mobile-phase conditions of 10% and 40% acetonitrile with 0.1% TFA.

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