823785-77-9Relevant academic research and scientific papers
Ruthenium- and platinum-catalyzed sequential reactions: Selective synthesis of fused polycyclic compounds from propargylic alcohols and alkenes
Nishibayashi, Yoshiaki,Yoshikawa, Masato,Inada, Youichi,Hidai, Masanobu,Uemura, Sakae
, p. 16066 - 16072 (2007/10/03)
A simple method for the preparation of fused polycyclic compounds by an intramolecular cyclization of propargylic alcohols bearing an alkene moiety at a suitable position has been developed, where the presence of both Ru and Pt catalysts promotes a sequence of catalytic cycles in the same medium. This sequential system can be applied to an intermolecular reaction between a propargylic alcohol and an alkene to obtain the corresponding bicyclo[3,1,0]hex-2-ene derivative. These sequential reactions provide a conceptually new type of cycloaddition system between propargylic alcohols and alkenes.
