82379-27-9

Upstream product

• 82399-66-4 (R)-3-Ethoxycarbonylmethyl-5-oxo-pyrrolidine-3-carboxylic acid 
• 82379-24-6 [(S)-3-(3-Diazo-2-oxo-propyl)-5-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester 
• 82379-25-7 3-((S)-3-tert-Butoxycarbonylamino-5-oxo-pyrrolidin-3-yl)-propionic acid methyl ester 
• 82379-22-4 (-)-(R)-Ethyl 3-(tert-butyloxycarbonylamino)-5-oxo-3-pyrrolidineacetate 
• 82379-23-5 (-)-(R)-3-(Tert-butyloxycarbonylamino)-5-oxo-3-pyrrolidineacetic acid 

Relevant academic research and scientific papers

SYNTHESIS AND ABSOLUTE CONFIGURATION OF THREE ISOMERIC SPIRO-BIS(2-PYRROLIDINONES)

Syntheses are described for three isomeric spiro-bis-(2-pyrrolidinones): 2,7-diazaspirononane-3,8-dione (II), 2,7-diazaspirononane-1,8-dione (IV) and 1,7-diazaspirononane-2,8-dione (VI).All the syntheses were carried out starting from 3-carboxy-5-oxo-3-pyrrolidineacetic acid (VIII) of known configuration, allowing the assignation of absolute configuration to compounds II, IV and VI synthetized through stereochemically unequivocal reaction steps.