82380-59-4Relevant academic research and scientific papers
SYNTHESIS OF AZETIDIN-3-ONES. STRUCTURE OF N-TOSYL-2-ETHYLAZETIDIN-3-ONE
Aliev, Z. G.,Atovmyan, L. O.,Sipyagin, A. M.,Kartsev, V. G.,Dobrokhotova, O. V.
, p. 390 - 395 (1987)
A one-step synthesis of azetidin-3-ones by intramolecular cyclization of 1-diazo-3-arenesulfamoylalkan-2-ones was developed.The yield of cyclic product increases to 70percent in the presence of an alkyl or benzyl substituent in the hydrocarbon chain of the diazoketone.The structure of N-tosyl-2-ethylazetidin-3-one was studied by x-ray diffraction analysis and it was shown that the four-membered ring has 15 deg inflection.
