824-35-1

Usage

Uses

Used in Pharmaceutical Industry:
Calcium salicylate is used as an anti-inflammatory and analgesic agent for the treatment of conditions such as arthritis, muscle pain, and joint inflammation. Its effectiveness in reducing pain and inflammation makes it a popular choice for inclusion in topical ointments and creams.
Used in Dental Industry:
In the dental field, calcium salicylate is utilized for its anti-inflammatory and analgesic properties. It is incorporated into dental products to help alleviate pain and reduce inflammation associated with dental procedures or conditions, enhancing patient comfort and promoting healing.
Overall, calcium salicylate's diverse applications in the pharmaceutical and dental industries highlight its importance as a therapeutic agent for managing pain and inflammation. Its ability to target the underlying causes of these symptoms through the inhibition of prostaglandin production makes it a valuable component in the development of effective treatments for various conditions.

InChI:InChI=1/2C7H6O3.Ca.2H2O/c2*8-6-4-2-1-3-5(6)7(9)10;;;/h2*1-4,8H,(H,9,10);;2*1H2/q;;+2;;/p-2

Upstream product

• 54-21-7 sodium salicylate 
• 14336-71-1 calcium chloride 

Downstream Products

• 69-72-7 salicylic acid 
• 6020-32-2 copper(II) salicylate dihydrate 

Relevant academic research and scientific papers

Alkaline-earth metal carboxylates characterized by 43Ca and 87Sr solid-state NMR: Impact of metal-amine bonding

A series of calcium and strontium complexes featuring aryl carboxylate ligands has been prepared and characterized by alkaline-earth (43Ca and 87Sr) solid-state NMR experiments in a magnetic field of 21.1 T. In the 11 compounds studied as part of this work, a range of coordination motifs are observed including nitrogen atom binding to Ca2+ and Sr 2+, a binding mode which has not been investigated previously by 43Ca or 87Sr solid-state NMR. 43Ca isotopic enrichment has enabled the full characterization of the 43Ca electric field gradient (EFG) and chemical shift tensors of the two calcium sites in calcium p-aminosalicylate (Ca(pams)), where both NMR interactions are affected by the presence of a nitrogen atom in the first coordination sphere of one of the metal sites. The 43Ca isotropic chemical shift is sensitive to the Ca-N distance as exemplified by the NMR parameters of a second form of Ca(pams) and density functional theory (DFT) calculations. Studies of the strontium analogue, Sr(pams), confirm a similar sensitivity of the 87Sr EFG tensor to the presence or absence of nitrogen in the first coordination sphere. To our knowledge, this is the first systematic 87Sr NMR study of strontium complexes featuring organic ligands. The |CQ(87Sr)| values are found to be sensitive to the coordination number about Sr2+. In general, this work has also established a larger data set of reliable experimental |CQ( 43Ca)| values which correlate well with those obtained using gauge-including projector-augmented-wave (GIPAW) DFT calculations. It is found that the use of a recently recommended quadrupole moment for 43Ca, -44.4 mbarn, improves the agreement with experimental values. This contribution lays the groundwork for the interpretation of 43Ca and 87Sr NMR spectra of more challenging systems, particularly where nitrogen-alkaline earth metal bonding is occurring.