82408-32-0

Basic information

• Product Name: (1-Hydroxy-2-oxo-2-phenyl-ethylsulfanyl)-acetic acid ethyl ester
• Synonyms: (1-Hydroxy-2-oxo-2-phenyl-ethylsulfanyl)-acetic acid ethyl ester
• CAS NO: 82408-32-0
• Molecular Weight: 254.307
• Mol File: 82408-32-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-Hydroxy-2-oxo-2-phenyl-ethylsulfanyl)-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1-Hydroxy-2-oxo-2-phenyl-ethylsulfanyl)-acetic acid ethyl ester(82408-32-0)
• EPA Substance Registry System: (1-Hydroxy-2-oxo-2-phenyl-ethylsulfanyl)-acetic acid ethyl ester(82408-32-0)

Safety Data

• Hazardous Substances Data: 82408-32-0(Hazardous Substances Data)

Upstream product

• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 623-51-8 ethyl 2-sulfanylacetate 

Downstream Products

• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 623-51-8 ethyl 2-sulfanylacetate 

Relevant articles and documents

Reactions of Thiols with Phenylglyoxal to Give Thiomandelic S-Esters Formation of Hemithioacetals and Their Rearrangement

Equilibrium constants Kh for the addition of 2-mercaptoethanol and glutathione to phenylglyoxal to form hemithioacetals were determined spectrophotometrically over the pH range 7-10.The observed Kh values decrease sigmoidally with pH as the thiol ionizes.Rearrangement of hemithioacetals formed from phenylglyoxal and various thiols was kinetically investigated.The rates increase with thiol concentration following a saturation curve to give Kh identical with the spectrophotometric value.The rearrangement is subject to general base catalysis.The solvent isotope effect on the rate of the rearrangement, kH2O/kd2O, is nearly 1.0; that on the equilibrium, KH2Oh/KD2Oh, is 0.38.The results strongly support the mechanism involving proton transfers through an enediol intermediate.