82418-40-4

Basic information

• Product Name: 1H-Imidazole,2-methyl-1-(2-propynyl)-(9CI)
• Synonyms: 1H-Imidazole,2-methyl-1-(2-propynyl)-(9CI)
• CAS NO: 82418-40-4
• Molecular Formula: C₇H₈N₂
• Molecular Weight: 120.154
• Product Categories: AMINETERTIARY
• Mol File: 82418-40-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Imidazole,2-methyl-1-(2-propynyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole,2-methyl-1-(2-propynyl)-(9CI)(82418-40-4)
• EPA Substance Registry System: 1H-Imidazole,2-methyl-1-(2-propynyl)-(9CI)(82418-40-4)

Safety Data

• Hazardous Substances Data: 82418-40-4(Hazardous Substances Data)

Upstream product

• 693-98-1 2-methylimidazole 
• 106-96-7 propargyl bromide 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 82418-28-8 2-Butyl-2-(2,4-dichlorphenyl)-3-methyl-4-(2-methyl-1-imidazolyl)-3-butennitril 
• 82418-29-9 2-Butyl-2-(3,4-dichlorphenyl)-3-methyl-4-(2-methyl-1-imidazolyl)-3-butennitril 
• 82418-26-6 3-Methyl-4-(2-methyl-1-imidazolyl)-2,2-diphenyl-3-butennitril 

Relevant articles and documents

Copper-Catalyzed Hydroamination of N-Allenylazoles: Access to Amino-Substituted N-Vinylazoles

Building on mechanistic studies, the innate capability of azoles to act as a directing group has been exploited to design an efficient and simple procedure for the hydroamination of N-allenylazoles with secondary amines. The reaction proceeds under mild conditions by copper(I) catalysis yielding the corresponding original linear E allylic amines with total regio- and stereoselectivity. Density Functional Theory (DFT) calculations offer a mechanistic explanation of the significantly higher reactivity of N-allenyl-(1,2)-azoles compared to their 1,3-analogues as a result of the reaction-enhancing coordination of the pyridine-like nitrogen to the copper center. (Figure presented.).