82420-34-6

Basic information

• Product Name: 4-BROMO-2-NITROBENZYL BROMIDE
• Synonyms: 4-BROMO-2-NITROBENZYL BROMIDE;4-bromo-1-(bromomethyl)-2-nitrobenzene;Benzene, 4-broMo-1-(broMoMethyl)-2-nitro-
• CAS NO: 82420-34-6
• Molecular Formula: C₇H₅Br₂NO₂
• Molecular Weight: 294.93
• Mol File: 82420-34-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 325.792 °C at 760 mmHg
• Flash Point: 150.834 °C
• Appearance: /
• Density: 2.007 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.643
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-BROMO-2-NITROBENZYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-NITROBENZYL BROMIDE(82420-34-6)
• EPA Substance Registry System: 4-BROMO-2-NITROBENZYL BROMIDE(82420-34-6)

Safety Data

• Hazardous Substances Data: 82420-34-6(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-nitrobenzyl bromide is a chemical compound that is used in organic synthesis and pharmaceutical research. It is a brominated benzyl derivative with a nitro group attached to the aromatic ring. 4-BROMO-2-NITROBENZYL BROMIDE is often used as a building block in the synthesis of various biologically active molecules and pharmaceutical compounds. It is also used in the preparation of other chemical compounds, such as dyes and polymers. 4-Bromo-2-nitrobenzyl bromide is known to be a potentially hazardous chemical and should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C7H5Br2NO2/c8-4-5-1-2-6(9)3-7(5)10(11)12/h1-3H,4H2

Upstream product

• 59382-59-1 2-methyl-3-nitro-benzoic acid methyl ester 
• 60956-26-5 4-bromo-2-nitrotoluene 
• 22996-19-6 (4-bromo-2-nitrophenyl)methanol 

Downstream Products

• 5551-12-2 4-bromo-2-nitrobenzaldehyde 
• 651780-40-4 (4-bromo-2-nitrobenzyl)(methyl)sulfane 
• 651780-34-6 (4-bromo-2-nitrophenyl)methyl 4-fluorophenyl sulfide 
• 1392125-65-3 (S)-7-bromo-3-methyl-2,3-dihydrooxazolo[3,2-b]indazole 
• 1392125-70-0 (S)-3-ethyl-7-(3-methoxyphenyl)-12-methyl-12,13-dihydro-[1,2,3]triazolo[1',5':5,6][1,2,5]triazepino[1,2-a]indazol-10(4H)-one 
• 1188442-69-4 C₂₅H₂₉N₃OSi 
• 1188442-73-0 C₂₃H₂₃N₃O₂ 
• 1188442-75-2 C₂₂H₂₃N₅O 
• 1188442-60-5 C₂₂H₂₂N₄O 
• 1188442-78-5 C₂₂H₂₂N₄O₂ 
• 1188442-71-8 C₂₂H₂₁N₃O 
• 1188442-22-9 C₂₁H₂₀N₄O 
• 1188442-63-8 C₂₁H₂₀N₄O 
• 1188442-83-2 C₂₁H₂₀N₄O 

Relevant articles and documents

Synthesis of mono-functionalized S-diazocines via intramolecular Baeyer-Mills reactions

Herein we report a reliable method to synthesize mono-functionalized S-diazocines in reproducible yields via intramolecular Baeyer-Mills reactions. Diazocines exhibit excellent photoswitchable properties. As opposed to azobenzenes they are more stable in

METHOD FOR PRODUCING 2-FLUORO-4-BORONO-L-PHENYLALANINE, AND A DERIVATIVE OF 2-FLUORO-4-BORONO-L-PHENYLALANINE

The present invention provides a method for producing 2-fluoro-4-borono-L-phenylalanine, and aderivative of 2-fluoro-4-borono-L-phenylalanine. The invention is to prepare and use a compound represented by the following formula. In the formula, R1/su

Design, synthesis, and pharmacological evaluation of fused β-homophenylalanine derivatives as potent DPP-4 inhibitors

Dipeptidyl peptidase-4 (DPP-4) inhibitors are accepted as a favorable class of agents for the treatment of type 2 diabetes. Herein, a series of fused β-homophenylalanine derivatives as novel DPP-4 inhibitors were designed, synthesized, and evaluated for their inhibitory activities against DPP-4. Most of them displayed excellent DPP-4 inhibitory activities and good selectivity. Among them, 9aa, 18a, and 18m also showed good efficacy in an oral glucose tolerance test (OGTT) in ICR mice. Moreover, when dosed 8 h prior to glucose challenge, 18m showed significantly greater potency than sitagliptin. It thus provides potential candidates for the further development into potent drugs targeting DPP-4.