82436-19-9

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

Synonyms are alternative names for a chemical compound, often used to describe the same substance in different contexts or by different organizations.

Explanation

This describes the appearance of the compound in its pure form, which is a solid with a color ranging from white to light yellow.

Explanation

The compound is used as a starting material or building block in the creation of different pharmaceutical agents.

Explanation

The compound is utilized in the development of drugs that have the potential to reduce inflammation and alleviate pain.

Explanation

The compound has been studied for its possible use in treating a range of health issues, making it valuable for drug discovery and development.

Explanation

Due to the potential hazards and toxicities associated with the compound, care should be taken when handling and using it to minimize risks to health and safety.

Explanation

The compound consists of a 1,3-dithiolane ring, which is a five-membered ring containing two sulfur atoms, and a meta-methoxyphenyl group attached to the ring.

Synonyms

Novasal

Physical State

White to light yellow solid

Pharmaceutical Industry Use

Precursor in the synthesis of various drugs

Application

Building block for anti-inflammatory and analgesic drugs

Potential Medical Applications

Treatment of various medical conditions

Hazards and Toxicities

Caution required in handling and use

Chemical Structure

1,3-Dithiolane with a m-methoxyphenyl group

InChI:InChI=1/C10H12OS2/c1-11-9-4-2-3-8(7-9)10-12-5-6-13-10/h2-4,7,10H,5-6H2,1H3

Upstream product

• 540-63-6 ethane-1,2-dithiol 
• 591-31-1 3-methoxy-benzaldehyde 
• 1175098-13-1 2-(3-methoxyphenyl)-5,5-dimethyl-1,3-dioxane 
• 2403-47-6 3-methoxybenzaldehyde diethyl acetal 

Downstream Products

• 586-38-9 3-Methoxybenzoic acid 
• 591-31-1 3-methoxy-benzaldehyde 
• 10259-22-0 ethyl 3-methoxybenzoate 

Relevant academic research and scientific papers

Phosphorylated Polyacrylonitrile Fibers as an Efficient and Greener Acetalization Catalyst

A novel solid acid catalyst (PANEAPF) is developed by immobilization of phosphoric acid on polyacrylonitrile fiber through covalent bonding. Various characterization techniques such as elemental analysis (EA), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), etc. are utilized to confirm the successful grafting and the stability of the fiber catalysts during application. PANEAPF shows high catalytic activity in the acetalization of aldehydes owing to the high utilization efficiency of its functionalized acid sites. In addition, the strong polarity micro-environment in the surface layers of PANEAPF make it highly suitable for catalytic application in both water and alcohol. Furthermore, the fiber catalyst can be applied to the acetalization of aldehydes in a continuous-flow process at room temperature, and shows excellent reactivity and superior recyclability (over 20 times). The many advantages of PANEAPF such as simple preparation, convenient regulation of acid amount, high durability, and eco-friendly process make it very attractive for fixed-bed reactors in the chemical industry.

Sulfur-Directed Ligand-Free C-H Borylation by Iridium Catalysis

An iridium-catalyzed ortho C-H borylation reaction directed by cyclic dithioacetal moiety is disclosed. A series of borylation products were obtained in moderate to good yields under mild conditions in exclusive mono- and ortho-regioselectivity. Thus, the 1,3-dithiane or 1,3-dithiolane group serves as a remarkable effective directing group for C-H borylation without any ligand assistance. The further transformations of the borylation products are also carried out to change boryl group to other functional groups.

Sulfonated polyanthracene-catalyzed highly efficient and chemoselective thioacetalization of carbonyl compounds and transthioacetalization of acetals and acylals

A straightforward and highly efficient procedure for the thioacetalization of a variety of aldehydes and transthioacetalization of acylals and acetals in good to excellent yields using catalytic amounts of sulfonated polyanthracene (S-PAT) is reported. Th

Solid-supported odorless reagents for the dithioacetalization of aldehydes and ketones

A solid supported, odorless reagent for the dithioacetalization of aldehydes and ketones has been developed. The new reagent provides the dimercaptoalkane equivalent in combination with stoichiometric amounts of immobilized acid and enables the formation of dithianes and dithiolanes from aldehydes without any additives in good to very good yields with high purities. The reaction is chemoselective for aldehydes, but ketones can be reacted to the corresponding dithioketals if an additional Lewis acid such as BF3is added.

Oxidative cross-esterification of dithiolanes with alcohols through a cross-dehydrogenative coupling (CDC)/deprotection sequence

An unprecedented oxidative cross-esterification in an equimolar mixture of dithiolanes, alcohols and water through a CDC/deprotection sequence has been developed. The reaction itself features simple experimental procedures under very mild conditions and offers a new strategic protocol for the direct and efficient synthesis of structurally diverse esters.

An efficient method for chemoselective thioacetalization of aldehydes in the presence of a catalytic amount of acidic ionic liquid under solvent-free conditions

A water-stable Br?nsted acidic ionic liquid with an alkane sulfonic acid group was synthesized. This ionic liquid catalyzed the thioacetalization reaction smoothly to afford 1,3-dithianes in excellent yield and less time. In this article we describe a mil

Efficient method for thioacetalization of carbonyl compounds in the presence of a catalytic amount of benzyltriphenylphosphonium tribromide (BTPTB) under solvent-free conditions

A variety of carbonyl compounds have been successfully converted to the corresponding thioacetal derivatives in good to excellent yields on reaction of carbonyl compounds with 1,2-ethanedithiole, 1,3-propanedithiol, and ethylthiol in the presence of a cat

Application of BU4N+HSO4- as an ionic liquid and acid catalyst for thioacetalization of aldehydes and ketones

A variety of carbonyl containing compounds have been successfully reacted with 1,2-ethanedithiol in a thioacetylization reaction using tetrabutylammonium hydrogensulfate as a mild and efficient catalyst. Aldehydes and ketones react with good to excellent

An efficient method for thioacetalization of carbonyl compounds in the presence of a catalytic amount of benzyltriphenylphosphonium tribromide under solvent-free conditions

A variety of carbonyl compounds have been successfully converted to the corresponding thioacetal derivatives in good to excellent yields on the reaction of carbonyl compounds with 1,2-ethanedithiole, 1,3-propanedithiol, and ethanethiol in the presence of

Chemoselective and solvent-free thioacetalization of aldehydes by a catalytic amount of NBS

A chemoselective, straightforward, and rapid method for thioacetalization of aldehydes by use of 1,2-ethandithiol and a catalytic amount of N-bromosuccinimide under solvent-free conditions is reported. The reaction takes place in excellent yields and shor