82439-20-1

Basic information

• Product Name: 3-Pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-bis(2,4,6-trimethylphenyl)-
• CAS NO: 82439-20-1
• Molecular Formula: C26H30N2O2
• Molecular Weight: 402.536
• Mol File: 82439-20-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-bis(2,4,6-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-bis(2,4,6-trimethylphenyl)-(82439-20-1)
• EPA Substance Registry System: 3-Pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-bis(2,4,6-trimethylphenyl)-(82439-20-1)

Safety Data

• Hazardous Substances Data: 82439-20-1(Hazardous Substances Data)

Upstream product

• 19359-16-1 2',4',6'-Trimethyl-acetessigsaeureanilid 

Relevant articles and documents

Preparation and Antiinflammatory Activity of 2- and 4-Pyridones

Several N-alkyl- and N-arylacetoamides have been self-condensed to form pyridones.N-Alkylacetoacetamides give 2-pyridones, while N-arylacetoamides give 4-pyridones.In an attempt to develop nonacidic, nonsteroidal antiinflammatory agents, the pyridones were tested in a carrageenan-induced pedal edema assay in rats.While the 2-pyridones were not active, 9 of 17 4-pyridones tested were active, and one compound (4g) had antiinflammatory efficacy in a dose-response assay (ED50 values).Most compounds were considered nontoxic by determination of approximate LD50 values in mice by a standard multidimensional observational assay.