82439-87-0

Basic information

• Product Name: 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide
• Synonyms: 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide;1-(4-nitrobenzyl)-4-hydroxy-1H-imidazole-5-carboxamide
• CAS NO: 82439-87-0
• Molecular Formula: C₁₁H₁₀N₄O₄
• Molecular Weight: 262.22
• Mol File: 82439-87-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide(82439-87-0)
• EPA Substance Registry System: 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide(82439-87-0)

Safety Data

• Hazardous Substances Data: 82439-87-0(Hazardous Substances Data)

Usage

General Description

The chemical compound 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide, also known as NB-DADMe-5, is a derivative of the imidazole class of compounds. It is primarily used as a research tool in the field of biochemistry and pharmacology to study the structure and function of imidazole receptors. 3-(4-Nitrobenzyl)-5-hydroxy-3H-imidazole-4-carboxamide has been shown to exhibit activity as an agonist at the 5-hydroxytryptamine receptor, making it a potential candidate for drug development in the treatment of various neurological and psychiatric disorders. Its unique structure and pharmacological properties make it a valuable tool for understanding the role of imidazole receptors in cellular signaling pathways and neurotransmission.

Upstream product

• 93512-83-5 2-(4-nitrobenzyl)aminopropanediamide 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 85240-44-4 1-(4-nitrobenzyl)-4-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)oxy-1H-imidazole-5-carboxamide 
• 85252-48-8 1-(4-nitrobenzyl)-4-(2,3,4,6-tetra-o-acetyl-β-D-glucopyranosyl)oxy-1H-imidazole-5-carboxamide 
• 85240-56-8 methyl 1-O-[5-carbamoyl-1-(4-nitrobenzyl)imidazole-4-yl]-2,3,4-tri-O-acetyl-β-D-glucopyranuronate 
• 85240-49-9 1-(4-nitrobenzyl)-4-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)oxy-1H-imidazole-5-carboxamide 
• 85240-62-6 1-(4-nitrobenzyl)-4-(2,3,5-tri-O-acetyl-β-D-ribofuranosyloxy)-1H-imidazole-5-carboxamide 
• 1001165-58-7 3-(4-nitrobenzyl)-5-(tert-butyldimethylsilanyloxy)-3H-imidazole-4-carboxamide 

Relevant articles and documents

4-Carbamoylimidazolium-5-olate derivatives

There are provided compounds of the formula: STR1 wherein either R1 or R2 is a hydrogen atom, a hydroxy group, an acyloxy group, a phthalimido group or an acetamido group and the other is a hydrogen atom; either R3 or R4 is a hydroxy group or an acyloxy group and the other is a hydrogen atom; either R5 or R6 is a hydroxy group or an acyloxy group and the other is a hydrogen atom; either R7 or R8 is a hydrogen atom, a methyl group, a hydroxymethyl group, an acyloxymethyl group, an alkoxycarbonyl group, a group of the formula: STR2 (wherein X1 and X2 are a hydrogen atom or a lower alkyl group), or a carboxyl group and the other is a hydrogen atom; either R11 or R12 is a hydrogen atom, a hydroxy group or an acyloxy group and the other is a hydrogen atom; either R13 or R14 is a hydroxy group or an acyloxy group and the other is a hydrogen atom; either R15 or R16 is a methyl group, a hydroxymethyl group or an acyloxymethyl group and the other is a hydrogen atom; and a process for producing them. These compounds are useful as antitumor agents.