824424-71-7

Usage

Molecular structure

2,2-oxybis[benzene-4,1-diylnitrilo(E)methylylidene]bis(6-methoxyphenol) contains two benzene rings connected by a methylene bridge, with each benzene ring linked to a nitrile group and two 6-methoxyphenol groups.

Type of compound

It is a complex chemical compound and a bisphenol.

Usage

Commonly used in the production of epoxy resins, polycarbonate plastics, and thermal paper coatings.

Health and environmental concerns

It has raised concerns due to its potential for endocrine disruption and other adverse health effects, so it is important to handle it carefully and consider its potential impact on human health and the environment.

Upstream product

• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 101-80-4 4,4'-oxydiphenylene diamine 

Relevant academic research and scientific papers

Ether based flexible bis Schiff base fluorescent colorimetric chemosensors for selective and sensitive detection of HF2 ? ion

Two simple and low cost bis Schiff base fluorescent colorimetric chemosensors L1 and L2 have been designed and synthesized. These sensors could detect important anion HF2 ? by change in both absorption and fluorescence intensity in methanol tris HCl buffer (1:1 v/v) solution at physiological pH. The mechanism of selectivity and sensitivity of these receptors to HF2 ? has proposed to be on the basis of photo-induced electron transfer (PET), chelation enhanced fluoresence (CHEF) and hydrogen bonding mechanism, confirmed by FT-IR, 1H-NMR and ESI-mass spectra. Interestingly, chelation of HF2 ? to the receptors takes place in 1:2 ratio, which has been confirmed by job plots analysis, ESI-mass spectra, DFT and TD-DFT studies. The detection limits of the probes L1 and L2 for HF2 ? were determined to be 6.1 μM for L1 and 3.94 μM for L2 respectively, on the basis of 3σ/K. Importantly, the low detection limits of L1 and L2 for HF2 ?suggest that L1 and L2 are sensitive sensors for detection of these ions in drinking water. The receptors L1 and L2 can successfully applied for detection and quantification of HF2 ? in real samples. To the best of our knowledge this is the third report of fluorescent colorimetric chemosensors for HF2 ? ions.

Simple salicylaldimine-functionalized dipodal bis Schiff base chromogenic and fluorogenic chemosensors for selective and sensitive detection of Al3+ and Cr3+

Two salicylaldimine-functionalized dipodal bis Schiff base low cost fluorescent colorimetric chemosensors L1 (bis([4-(2-hydroxy-3-methoxybenzyl-ideneamino)phenyl]ether) and L2 (di[(4-phenylimino)4-diethylsalicyl-aldehyde]ether) have been designed and synt

Magnetic and luminescent binuclear double-stranded helicates

Three new binuclear helicates, [M2L2]·3DMF (M = Co(II), 1, Zn(II), 3) and [Cu2L2]·DMF·0. 4H2O (2), have been assembled using the helicand H2L that results from the 2:1 condensation reaction between o-vanillin and 4,4′-diaminodiphenyl ether. The metal ions within the binuclear helicates are tetracoordinated with a distorted tetrahedral geometry. Direct current magnetic characterization and EPR spectroscopy of the Co(II) derivative point to an easy axis type anisotropy for both Co(II) centers, with a separation of at least 55 K between the two doublets. Dynamic susceptibility measurements evidence slow relaxation of the magnetization in an applied dc field. Since the distance between the cobalt ions is quite large (11.59 A), this is attributed in a first instance to the intrinsic properties of each Co(II) center (single-ion magnet behavior). However, the temperature dependence of the relaxation rate and the absence of slow dynamics in the Zn(II)-doped sample suggest that neither the simple Orbach mechanism nor Raman or direct processes can account for the relaxation, and collective phenomena have to be invoked for the observed behavior. Finally, due to the rigidization of the two organic ligands upon coordination, the pure zinc derivative exhibits fluorescence emission in solution, which was analyzed in terms of fluorescence quantum yields and lifetimes.

Antitumor and antioxidant activities of the new synthesized azomethine derivatives: Experimental and theoretical investigations

In this study, the antioxidant property of eight new azomethine derivatives underwent theoretical and experimental investigations. Azomethines have antioxidant activity. This is the first time the molecular structures and antioxidant property of these derivatives have been studied. The molecular structures were optimized using Density functional theory (DFT). The Bond Dissociation Enthalpy (BDE), Mulliken Charges, NBO analysis, Ionization Potential (IP), Electron Affinities (EA), HOMO and LUMO energies, Hardness (η), Softness (S), Electronegativity (μ), Electrophilic Index (ω), Electron Donating Power (ω-), Electron Accepting Power (ω+), and Energy Gap (Eg) were calculated in order to deduce scavenging action of the eight new synthesized azomethines (DIA-3,4,5,6,7,8,9,10). Spin density calculations and NBO analysis were also carried out to understand the antioxidant activity mechanism. These molecules have high antioxidant potential due to the planarity and formation of intramolecular hydrogen bonds. Experimental investigations establish high antioxidant and antitumor activities of the synthesized azomethine derivatives.

Dinuclear Pd(II) complexes containing bis-O,N-bidentate Schiff base ligands: Synthesis, characterization, DFT study and application as Suzuki–Miyaura coupling catalysts

The reaction of binucleating Schiff base ligands with [PdCl2(PPh3)2] and [Pd(OAc)2] afforded a new family of binuclear palladium(II) Schiff base complexes of the type [Pd2(L)2] and [Pd2Cl2(PPh3)2(L)]. All the palladium complexes are air stable and fully characterized by elemental analysis, FT-IR, UV–Vis and 1H NMR spectral methods. These palladium(II) Schiff base complexes exhibit characteristic metal to ligand charge transfer (MLCT) transitions. Quantum mechanical calculations were also performed to investigate the electronic structure, assign the vibrational spectra and to determine the nature of the frontier molecular orbitals and absorption spectra of the above complexes. These palladium(II) Schiff base complexes exhibited good catalytic activity in the carbon–carbon Suzuki coupling reaction of different aryl halides using phenyl boronic acid.

Construction of NIR luminescent polynuclear lanthanide-based nanoclusters with sensing properties towards metal ions

Two types of 4- and 9-metal lanthanide-based nanoclusters [Ln2Zn2(L1)2(OAc)6] (Ln = Yb (1) and Er (2)) and [Yb9L2(L3)2(OAc)15(OH)8(H2O)2(DMF)] (3) were constructed using two Schiff base ligands that have long backbones with two and three phenyl groups. The molecular sizes of 1-2 and 3 are about 7 × 10 × 23 ? and 11 × 17 × 22 ?, respectively. These clusters exhibit typical NIR luminescence of lanthanide ions. Interestingly, 3 exhibits luminescent sensing of metal ions and exhibits high sensitivities towards Cd2+ and Co2+ ions at the ppm level.

O-vanillin Schiff base ligand and metal complex thereof, synthesis method and application

The invention provides an o-vanillin Schiff base ligand and a metal complex thereof. By researches on free radical scavenging capacity and antibacterial performances of the o-vanillin Schiff base ligand and two transition metal complexes thereof, great free radical scavenging capacity and antibacterial performances of the o-vanillin Schiff base ligand and the two transition metal complexes are preliminarily determined.

Organic synthesis by Twin Screw Extrusion (TSE): Continuous, scalable and solvent-free

Mechanochemistry provides a method to reduce or eliminate the use of solvents by carrying out reactions through the grinding of neat reagents. Until recently a significant drawback of this form of synthesis has been the limited ability to scale up. Howeve