824431-19-8

Basic information

• Product Name: Ethanol, 2-[bis[(1,5-dimethyl-1H-pyrazol-3-yl)methyl]amino]-
• CAS NO: 824431-19-8
• Molecular Formula: C14H23N5O
• Molecular Weight: 277.37
• Mol File: 824431-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanol, 2-[bis[(1,5-dimethyl-1H-pyrazol-3-yl)methyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-[bis[(1,5-dimethyl-1H-pyrazol-3-yl)methyl]amino]-(824431-19-8)
• EPA Substance Registry System: Ethanol, 2-[bis[(1,5-dimethyl-1H-pyrazol-3-yl)methyl]amino]-(824431-19-8)

Safety Data

• Hazardous Substances Data: 824431-19-8(Hazardous Substances Data)

Upstream product

• 5744-51-4 ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate 

Relevant articles and documents

Synthesis and enzyme inhibitory activities of some new pyrazole-based heterocyclic compounds

Three tridentate N,N-bis(3,5-dimethylpyrazol- 1-ylmethyl)-1-hydroxy-2- aminoethane (2), N,N-bis(3,5-dimethylpyrazol- 1-ylmethyl)-cyclohexylamine (3) and 2-[bis (1,5-dimethyl-1H-pyrazol-3-ylmethyl)amino]ethan-1-ol (4) are synthesized and spectroscopically characterized togetherwith 1-hydroxymethyl-3,5-dimethylpyrazole (1). These have been tested in inhibitory activities against various hyperactive enzymes like urease, β- glucuronidase, phosphodiesterase, α-chymotrypsin, acetylcholinesterase and butyrylcholinesterase. Compounds 1, 2 and 3 were found to be selective inhibitors of urease. Compound 4 was found to be selective inhibitor of butyrylcholinesterase. The nature of the junction between pyrazoles cycles determined the activities of these tripods. While the tripods are inactive towards urease or glucuronidase, they turn to be selective towards butyrylcholinesterase.